(5E)-5-({[2-(4-acetylpiperazin-1-yl)ethyl]amino}methylidene)-1-(4-fluorophenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione

Base Information

Chemical Name:(5E)-5-({[2-(4-acetylpiperazin-1-yl)ethyl]amino}methylidene)-1-(4-fluorophenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione
CAS No.:5287-13-8
Molecular Formula:C₁₄H₁₈N₂O₂S
Molecular Weight:278.375
Hs Code.:
DSSTox Substance ID:DTXSID20425418
ChEMBL ID:CHEMBL1511073

Synonyms:5287-13-8;AGN-PC-0LRUCN;MLS001213490;CHEMBL1511073;DTXSID20425418;HMS2860F06;STL043780;AKOS005697318;AKOS032389667;SMR000540564;(5E)-5-({[2-(4-acetylpiperazin-1-yl)ethyl]amino}methylidene)-1-(4-fluorophenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione

Suppliers and Price of (5E)-5-({[2-(4-acetylpiperazin-1-yl)ethyl]amino}methylidene)-1-(4-fluorophenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (5E)-5-({[2-(4-acetylpiperazin-1-yl)ethyl]amino}methylidene)-1-(4-fluorophenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.43g/cm³
XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:419.14273892
Heavy Atom Count:29
Complexity:713

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)N1CCN(CC1)CCN=CC2=C(N(C(=S)NC2=O)C3=CC=C(C=C3)F)O

Technology Process of (5E)-5-({[2-(4-acetylpiperazin-1-yl)ethyl]amino}methylidene)-1-(4-fluorophenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione

There total 5 articles about (5E)-5-({[2-(4-acetylpiperazin-1-yl)ethyl]amino}methylidene)-1-(4-fluorophenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5530-82-5
N-cyclohexyl-N'-tosyl-thiourea

: 5287-13-8
N-p-Toluolsulfonyl-N'-cyclohexyl-carbodiimid

Guidance literature:: With COCl₂; In chlorobenzene;
DOI:10.1021/jo01276a012

Reference yield:

: 70-55-3
toluene-4-sulfonamide

: 5287-13-8
N-p-Toluolsulfonyl-N'-cyclohexyl-carbodiimid

Guidance literature:: Multi-step reaction with 2 steps

1: aq. NaOH / acetone

2: COCl₂ / chlorobenzene

With sodium hydroxide; In chlorobenzene; acetone;
DOI:10.1021/jo01276a012

Reference yield:

: 1122-82-3
isothiocyanatocyclohexane

: 5287-13-8
N-p-Toluolsulfonyl-N'-cyclohexyl-carbodiimid

Guidance literature:: Multi-step reaction with 2 steps

1: aq. NaOH / acetone

2: COCl₂ / chlorobenzene

With sodium hydroxide; In chlorobenzene; acetone;
DOI:10.1021/jo01276a012