Technology Process of C44H53N7O10
There total 15 articles about C44H53N7O10 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C49H61N7O12;
With
trifluoroacetic acid;
In
dichloromethane;
at 0 - 20 ℃;
for 1.5h;
With
sodium hydrogencarbonate;
In
dichloromethane; water;
Product distribution / selectivity;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; 4-methyl-morpholine / 20 °C / Industry scale
2.1: water; lithium hydroxide / tetrahydrofuran; methanol / 10 - 20 °C / Industry scale
3.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; 4-methyl-morpholine / chloroform / 20 - 25 °C / Industry scale
4.1: water; lithium hydroxide / tetrahydrofuran; methanol / 10 - 20 °C / Industry scale
4.2: Industry scale
5.1: chloroformic acid ethyl ester; N-ethyl-N,N-diisopropylamine / chloroform / 10 - 20 °C / Industry scale
5.2: 0 °C / Industry scale
6.1: trifluoroacetic acid / dichloromethane / 1.5 h / 0 - 20 °C
With
4-methyl-morpholine; water; chloroformic acid ethyl ester; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; lithium hydroxide;
In
tetrahydrofuran; methanol; dichloromethane; chloroform;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: water; lithium hydroxide / tetrahydrofuran; methanol / 10 - 20 °C / Industry scale
2.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; 4-methyl-morpholine / chloroform / 20 - 25 °C / Industry scale
3.1: water; lithium hydroxide / tetrahydrofuran; methanol / 10 - 20 °C / Industry scale
3.2: Industry scale
4.1: chloroformic acid ethyl ester; N-ethyl-N,N-diisopropylamine / chloroform / 10 - 20 °C / Industry scale
4.2: 0 °C / Industry scale
5.1: trifluoroacetic acid / dichloromethane / 1.5 h / 0 - 20 °C
With
4-methyl-morpholine; water; chloroformic acid ethyl ester; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; lithium hydroxide;
In
tetrahydrofuran; methanol; dichloromethane; chloroform;