(R)-Sulconazole

Base Information

Chemical Name:(R)-Sulconazole
CAS No.:180185-77-7
Molecular Formula:C18H15 Cl3 N2 S
Molecular Weight:397.755
Hs Code.:
Mol file:180185-77-7.mol

Synonyms:1H-Imidazole,1-[2-[[(4-chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-, (R)-;(R)-Sulconazole

Suppliers and Price of (R)-Sulconazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (R)-Sulconazole

Chemical Property:

PSA：43.12000
LogP:6.51800

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (R)-Sulconazole

There total 10 articles about (R)-Sulconazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 131543-46-9,107-22-2
Glyoxal

: 1165796-83-7
(R)-2-((4-chlorobenzyl)thio)-2-(2,4-dichlorophenyl)ethanamine

: 180185-77-7,180185-78-8
(R)-sulconazole

Guidance literature:: With ammonium acetate; In methanol; water; at 95 ℃; for 16h; Inert atmosphere;
DOI:10.1021/ja903351a

Reference yield:

: 61318-90-9,180185-78-8
sulconazole

: 180185-77-7,180185-78-8
(R)-sulconazole

: 180185-78-8
(S)-sulconazole

Guidance literature:: With diethylamine; In hexane; isopropyl alcohol; Resolution of racemate;
DOI:10.1096/fj.201900443RR

Reference yield:

: 1165796-81-5
C₁₀H₁₁Cl₂NOS

: 180185-77-7,180185-78-8
(R)-sulconazole

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 20 °C

2: hydrogenchloride / methanol; water / 12 h / Inert atmosphere; Reflux

3: ammonium acetate / methanol / 16 h / Reflux

With hydrogenchloride; ammonium acetate; potassium carbonate; In methanol; water; N,N-dimethyl-formamide;
DOI:10.1016/j.tet.2012.01.048