2-(3-(benzyloxy)-4-methoxyphenyl)-N-(2-(3,4-dimethoxyphenyl)ethyl)acetamide

Base Information

Chemical Name:2-(3-(benzyloxy)-4-methoxyphenyl)-N-(2-(3,4-dimethoxyphenyl)ethyl)acetamide
CAS No.:18028-10-9
Molecular Formula:C26H29 N O5
Molecular Weight:435.5122
Hs Code.:
Mol file:18028-10-9.mol

Synonyms:Acetamide,2-[3-(benzyloxy)-4-methoxyphenyl]-N-(3,4-dimethoxyphenethyl)- (6CI,8CI); NSC261040

Suppliers and Price of 2-(3-(benzyloxy)-4-methoxyphenyl)-N-(2-(3,4-dimethoxyphenyl)ethyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2-(3-(benzyloxy)-4-methoxyphenyl)-N-(2-(3,4-dimethoxyphenyl)ethyl)acetamide

Chemical Property:

Vapor Pressure:3.02E-16mmHg at 25°C
Boiling Point:639.4°Cat760mmHg
Flash Point:340.5°C
Density:1.15g/cm³

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-(3-(benzyloxy)-4-methoxyphenyl)-N-(2-(3,4-dimethoxyphenyl)ethyl)acetamide

There total 5 articles about 2-(3-(benzyloxy)-4-methoxyphenyl)-N-(2-(3,4-dimethoxyphenyl)ethyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 54313-33-6
2-(3-(benzyloxy)-4-methoxyphenyl)acetyl chloride

: 120-20-7
2-(3,4-dimethoxyphenyl)-ethylamine

: 18028-10-9
N-(3-Benzyloxy-4-methoxy-phenyl)-N-(3,4-dimethoxy-phenaethyl)-acetamid

Guidance literature:: With sodium carbonate; In dichloromethane; water; at 20 ℃; for 2h;
DOI:10.1021/jo061810h

Reference yield:

: 5487-33-2
O-benzylhomoisovanillic acid

: 18028-10-9
N-(3-Benzyloxy-4-methoxy-phenyl)-N-(3,4-dimethoxy-phenaethyl)-acetamid

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 2 h / 20 °C

2: sodium carbonate / dichloromethane; water / 2 h / 20 °C

With oxalyl dichloride; sodium carbonate; N,N-dimethyl-formamide; In dichloromethane; water;
DOI:10.1021/jo061810h

Reference yield:

: 621-59-0
isovanillin

: 18028-10-9
N-(3-Benzyloxy-4-methoxy-phenyl)-N-(3,4-dimethoxy-phenaethyl)-acetamid

Guidance literature:: Multi-step reaction with 5 steps

1.1: potassium carbonate / acetone / 6 h / Heating

2.1: acetic acid; ethylenediamine / 20 °C

3.1: sodium tetrahydroborate / ethanol / 20 °C

3.2: AcOH; NaNO₂; DMSO / 20 °C

4.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 2 h / 20 °C

5.1: sodium carbonate / dichloromethane; water / 2 h / 20 °C

With sodium tetrahydroborate; oxalyl dichloride; sodium carbonate; potassium carbonate; acetic acid; ethylenediamine; N,N-dimethyl-formamide; In ethanol; dichloromethane; water; acetone; 2.1: Knoevenagel reaction;
DOI:10.1021/jo061810h