3-Pyridinecarboxaldehyde,4,6-diamino-(9CI)

Base Information

• Chemical Name: 3-Pyridinecarboxaldehyde,4,6-diamino-(9CI)
• CAS No.: 179343-43-2
• Molecular Formula: C6H7 N3 O
• Molecular Weight: 137.13928
• Hs Code.: 2933399090
• Mol file: 179343-43-2.mol

Synonyms:4,6-Diamino-3-pyridinecarboxaldehyde

Chemical Property of 3-Pyridinecarboxaldehyde,4,6-diamino-(9CI)

Chemical Property:

• PSA: 82.73000
• LogP: 0.56980
• Storage Temp.: 2-8°C

Purity/Quality:

98%Min ^*data from raw suppliers

4,6-Diaminonicotinaldehyde 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Pyridinecarboxaldehyde,4,6-diamino-(9CI)

There total 1 articles about 3-Pyridinecarboxaldehyde,4,6-diamino-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4-diamino-5-cyanopyridine (75776-47-5) → 4,6-Diaminonicotinaldehyde (179343-43-2)

Guidance literature:

With formic acid; hydrogen; W-7 Raney-Ni; In ethanol; at 20 ℃; for 216h; under 3102.97 Torr;

DOI:10.1021/jm000148t

Reference yield: 96.0%

3,5-dimethoxyphenylacetonitrile (13388-75-5) + 4,6-Diaminonicotinaldehyde (179343-43-2) → 3-(3,5-Dimethoxyphenyl)-1,6-naphthyridine-2,7-diamine (293301-09-4)

Guidance literature:

With sodium; In 2-ethoxy-ethanol; for 0.5h; Heating;

DOI:10.1039/b002599m

Reference yield:

2,6-dichlorophenylacetonitrile (3215-64-3) + 4,6-Diaminonicotinaldehyde (179343-43-2) → 2-(2,6-dichlorophenyl)acetamide (78433-88-2)

Guidance literature:

With sodium; In 2-ethoxy-ethanol;

upstream raw materials:

2,4-diamino-5-cyanopyridine

Downstream raw materials:

3-(3,5-Dimethoxyphenyl)-1,6-naphthyridine-2,7-diamine

3-(2,6-Dichlorophenyl)-1,6-naphthyridine-2,7-diamine

2-(2,6-dichlorophenyl)acetamide

2,7-Difluoro-3-(3,5-dimethoxyphenyl)-1,6-naphthyridine

Refernces

• 1、 -. "Naphthyridinones for inhibiting protein tyrosine kinase and cell cycle kinase mediated cellular proliferation". . . Retrieved 2008/06/13.