3,3-bis(trifluoromethyl)-1,1,1-tris{p-(trifluoromethyl)phenyl-3H-2,1-benzoxastibole

Base Information

• Chemical Name: 3,3-bis(trifluoromethyl)-1,1,1-tris{p-(trifluoromethyl)phenyl-3H-2,1-benzoxastibole
• CAS No.: 119274-13-4
• Molecular Formula: C₃₀H₁₆F₁₅OSb
• Molecular Weight: 799.182
• Mol file: 119274-13-4.mol

Synonyms:3,3-bis(trifluoromethyl)-1,1,1-tris{p-(trifluoromethyl)phenyl-3H-2,1-benzoxastibole

Chemical Property of 3,3-bis(trifluoromethyl)-1,1,1-tris{p-(trifluoromethyl)phenyl-3H-2,1-benzoxastibole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,3-bis(trifluoromethyl)-1,1,1-tris{p-(trifluoromethyl)phenyl-3H-2,1-benzoxastibole

There total 1 articles about 3,3-bis(trifluoromethyl)-1,1,1-tris{p-(trifluoromethyl)phenyl-3H-2,1-benzoxastibole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

tris{p-(trifluoromethyl)phenyl}antimony dibromide (119274-21-4) + lithium 1,1,1,3,3,3-hexafluoro-2-(2-lithiophenyl)-2-propoxide (70091-67-7) → 3,3-bis(trifluoromethyl)-1,1,1-tris{p-(trifluoromethyl)phenyl-3H-2,1-benzoxastibole (119274-13-4)

Guidance literature:

In tetrahydrofuran; hexane; stirring (N2 atmosphere, 20 h, room temp.), quenching (excess cold H2O); extn. (Et2O), evapn., chromy. (ethyl acetate/hexane), crystn. (C6H6), elem. anal.;

DOI:10.1021/ja00188a049

Reference yield:

3,3-bis(trifluoromethyl)-1,1,1-tris{p-(trifluoromethyl)phenyl-3H-2,1-benzoxastibole (119274-13-4) + 4-chlorophenyl lithium (14774-78-8) → 3,3-bis(trifluoromethyl)-1-(p-chlorophenyl)-1,1-bis{p-(trifluoromethyl)phenyl}-3H-2,1-benzoxastibole (119274-20-3)

Guidance literature:

In diethyl ether; stirring (N2 atmosphere, room temp., 30 min), quenching (AcOH/H2O); TLC, elem. anal.;

DOI:10.1021/ja00188a049

Reference yield:

3,3-bis(trifluoromethyl)-1,1,1-tris{p-(trifluoromethyl)phenyl-3H-2,1-benzoxastibole (119274-13-4) + p-tolyllithium (2417-95-0) → 3,3-bis(trifluoromethyl)-1-(p-methylphenyl)-1,1-bis{p-(trifluoromethyl)phenyl}-3H-2,1-benzoxastibole (119274-16-7)

Guidance literature:

In diethyl ether; stirring (N2 atmosphere, room temp., 30 min), quenching (AcOH/H2O); TLC, elem. anal.;

DOI:10.1021/ja00188a049

upstream raw materials:

tris{p-(trifluoromethyl)phenyl}antimony dibromide

lithium 1,1,1,3,3,3-hexafluoro-2-(2-lithiophenyl)-2-propoxide

Downstream raw materials:

3,3-bis(trifluoromethyl)-1-(p-chlorophenyl)-1,1-bis{p-(trifluoromethyl)phenyl}-3H-2,1-benzoxastibole

3,3-bis(trifluoromethyl)-1-(p-methylphenyl)-1,1-bis{p-(trifluoromethyl)phenyl}-3H-2,1-benzoxastibole

3,3-bis(trifluoromethyl)-1-(p-methoxyphenyl)-1,1-bis{p-(trifluoromethyl)phenyl}-3H-2,1-benzoxastibole