Methanesulfonic acid 4-methanesulfonyloxy-2-[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-butyl ester

Base Information

• Chemical Name: Methanesulfonic acid 4-methanesulfonyloxy-2-[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-butyl ester
• CAS No.: 1027191-56-5
• Molecular Formula: C₁₄H₂₀O₇S₂
• Molecular Weight: 364.441
• Mol file: 1027191-56-5.mol

Synonyms:Methanesulfonic acid 4-methanesulfonyloxy-2-[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-butyl ester

Chemical Property of Methanesulfonic acid 4-methanesulfonyloxy-2-[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methanesulfonic acid 4-methanesulfonyloxy-2-[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-butyl ester

There total 2 articles about Methanesulfonic acid 4-methanesulfonyloxy-2-[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-[(4-methoxyphenyl)methylene]-1,4-butanediol (131188-71-1) + methanesulfonyl chloride (124-63-0) → Methanesulfonic acid 4-methanesulfonyloxy-2-[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-butyl ester (1027191-56-5)

Guidance literature:

With triethylamine; In benzene; at 0 - 5 ℃; for 6h;

DOI:10.1021/jm000083u

Reference yield:

(E)-3-(4-methoxybenzylidene)dihydrofuran-2(3H)-one → Methanesulfonic acid 4-methanesulfonyloxy-2-[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-butyl ester (1027191-56-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 93 percent / LiAlH₄ / diethyl ether / 0.75 h

2: Et₃N / benzene / 6 h / 0 - 5 °C

With lithium aluminium tetrahydride; triethylamine; In diethyl ether; benzene; 1: reductive ring opening / 2: mesylation;

DOI:10.1021/jm000083u

Reference yield:

diethylaminopropylamine (104-78-9) + Methanesulfonic acid 4-methanesulfonyloxy-2-[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-butyl ester (1027191-56-5) → Diethyl-(3-{3-[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-pyrrolidin-1-yl}-propyl)-amine

Guidance literature:

With triethylamine; In benzene; for 10h; Heating;

DOI:10.1021/jm000083u

upstream raw materials:

2-[(4-methoxyphenyl)methylene]-1,4-butanediol

methanesulfonyl chloride