(Z)-diethyl 2-hydroxy-6-(4-methoxy benzyloxy)-4-methyl hex-4-enyl phosphonate

Base Information

Chemical Name:(Z)-diethyl 2-hydroxy-6-(4-methoxy benzyloxy)-4-methyl hex-4-enyl phosphonate
CAS No.:1227307-15-4
Molecular Formula:C₁₉H₃₁O₆P
Molecular Weight:386.425
Hs Code.:

Synonyms:(Z)-diethyl 2-hydroxy-6-(4-methoxy benzyloxy)-4-methyl hex-4-enyl phosphonate

Suppliers and Price of (Z)-diethyl 2-hydroxy-6-(4-methoxy benzyloxy)-4-methyl hex-4-enyl phosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (Z)-diethyl 2-hydroxy-6-(4-methoxy benzyloxy)-4-methyl hex-4-enyl phosphonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (Z)-diethyl 2-hydroxy-6-(4-methoxy benzyloxy)-4-methyl hex-4-enyl phosphonate

There total 5 articles about (Z)-diethyl 2-hydroxy-6-(4-methoxy benzyloxy)-4-methyl hex-4-enyl phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 1227307-23-4
(Z)-2-(4-(4-methoxybenzyloxy)-2-methylbut-2-enyl)oxirane

: 762-04-9
phosphonic acid diethyl ester

: 1227307-15-4
(Z)-diethyl 2-hydroxy-6-(4-methoxy benzyloxy)-4-methyl hex-4-enyl phosphonate

Guidance literature:: phosphonic acid diethyl ester; With n-butyllithium; In tetrahydrofuran; hexane; at -78 - -60 ℃; for 0.5h; Inert atmosphere;

(Z)-2-(4-(4-methoxybenzyloxy)-2-methylbut-2-enyl)oxirane; With boron trifluoride diethyl etherate; In tetrahydrofuran; hexane; at -78 ℃; for 6h; Inert atmosphere;

With water; sodium hydrogencarbonate; In tetrahydrofuran; hexane; at -78 - 20 ℃;
DOI:10.1021/ol100665m

Reference yield:

: 1227307-14-3
(Z)-1-chloro-6-(4-methoxybenzyloxy)-4-methylhex-4-en-2-ol

: 1227307-15-4
(Z)-diethyl 2-hydroxy-6-(4-methoxy benzyloxy)-4-methyl hex-4-enyl phosphonate

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium hydroxide / ethanol / 20 h / 0 °C

2.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C

2.2: 6 h / -78 °C

With n-butyllithium; potassium hydroxide; In tetrahydrofuran; ethanol; hexane;
DOI:10.1002/chem.201202553

Reference yield:

: 612090-71-8
(Z)-1-((3-iodobut-2-enyloxy)methyl)-4-methoxybenzene

: 1227307-15-4
(Z)-diethyl 2-hydroxy-6-(4-methoxy benzyloxy)-4-methyl hex-4-enyl phosphonate

Guidance literature:: Multi-step reaction with 3 steps

1.1: n-butyllithium / hexane; toluene / 0.5 h / -85 °C

1.2: 0.25 h

2.1: potassium hydroxide / ethanol / 20 h / 0 °C

3.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C

3.2: 6 h / -78 °C

With n-butyllithium; potassium hydroxide; In tetrahydrofuran; ethanol; hexane; toluene;
DOI:10.1002/chem.201202553