methyl 6-fluoro-7-hydroxy-3-methyl-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate

Base Information

Chemical Name:methyl 6-fluoro-7-hydroxy-3-methyl-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate
CAS No.:1335116-86-3
Molecular Formula:C₁₉H₁₃F₄NO₃
Molecular Weight:379.311
Hs Code.:

Synonyms:methyl 6-fluoro-7-hydroxy-3-methyl-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate

Suppliers and Price of methyl 6-fluoro-7-hydroxy-3-methyl-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 6-fluoro-7-hydroxy-3-methyl-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 6-fluoro-7-hydroxy-3-methyl-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate

There total 4 articles about methyl 6-fluoro-7-hydroxy-3-methyl-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67-56-1
methanol

: 1335116-85-2
6-fluoro-7-hydroxy-3-methyl-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylic acid

: 1335116-86-3
methyl 6-fluoro-7-hydroxy-3-methyl-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate

Guidance literature:: 6-fluoro-7-hydroxy-3-methyl-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 0 - 20 ℃;

methanol; In dichloromethane; at 20 ℃;

Reference yield:

: 454-89-7
3-Trifluoromethylbenzaldehyde

: 1335116-86-3
methyl 6-fluoro-7-hydroxy-3-methyl-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: ethanol / Reflux

1.2: 20 °C / Reflux

2.1: hydrogen bromide; acetic acid / 120 h / Reflux

3.1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 0 - 20 °C

3.2: 20 °C

With oxalyl dichloride; hydrogen bromide; acetic acid; N,N-dimethyl-formamide; In ethanol; dichloromethane;

Reference yield:

: 64465-53-8
4-fluoro-3-methoxyaniline

: 1335116-86-3
methyl 6-fluoro-7-hydroxy-3-methyl-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: ethanol / Reflux

1.2: 20 °C / Reflux

2.1: hydrogen bromide; acetic acid / 120 h / Reflux

3.1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 0 - 20 °C

3.2: 20 °C

With oxalyl dichloride; hydrogen bromide; acetic acid; N,N-dimethyl-formamide; In ethanol; dichloromethane;