2,3,6,7-Tetrahydrofuro[2,3-f][1]benzofuran-4-carbaldehyde

Base Information

Chemical Name:2,3,6,7-Tetrahydrofuro[2,3-f][1]benzofuran-4-carbaldehyde
CAS No.:178557-13-6
Molecular Formula:C11H10O3
Molecular Weight:190.199
Hs Code.:
European Community (EC) Number:830-839-5
DSSTox Substance ID:DTXSID70443026
Wikidata:Q82260699
Mol file:178557-13-6.mol

Synonyms:178557-13-6;2,3,6,7-tetrahydrofuro[2,3-f][1]benzofuran-4-carbaldehyde;4-FORMYL-2,3,6,7-TETRAHYDROBENZO[1,2-B:4,5-B']DIFURAN;Benzo[1,2-b:4,5-b']difuran-4-carboxaldehyde, 2,3,6,7-tetrahydro-;4-Formyl-2,3,6,7-tetrahydrobenzo[1,2-b:4,5-b]difuran;4-Formyl-2,3,6,7-Tetrahydrobenzo[1,2-B:4,5-B/']Difuran;CID 10655281;SCHEMBL2128017;DTXSID70443026;2,3,6,7-Tetrahydro-benzo[1,2-b;4,5-b']difuran-4-carbaldehyde;MFCD09743794;AKOS004111180;AG-E-28745;FT-0695621;EN300-736566;A812379;AT-057/43485260;Z1198221874;2,3,6,7-tetrahydrofuro[2,3-f]benzofuran-4-carbaldehyde;4-Formyl-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']difuran;4,10-dioxatricyclo[7.3.0.0,3,7]dodeca-1,3(7),8-triene-2-carbaldehyde;4,10-dioxatricyclo[7.3.0.0?,?]dodeca-1,3(7),8-triene-2-carbaldehyde

Suppliers and Price of 2,3,6,7-Tetrahydrofuro[2,3-f][1]benzofuran-4-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2,3,6,7-Tetrahydrofuro[2,3-f][1]benzofuran-4-carbaldehyde

Chemical Property:

PSA：35.53000
LogP:1.36890
XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:190.062994177
Heavy Atom Count:14
Complexity:241

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC2=C(C3=C(C=C21)OCC3)C=O

Technology Process of 2,3,6,7-Tetrahydrofuro[2,3-f][1]benzofuran-4-carbaldehyde

There total 5 articles about 2,3,6,7-Tetrahydrofuro[2,3-f][1]benzofuran-4-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 4885-02-3
Dichloromethyl methyl ether

: 81926-24-1
4,10-dioxatricyclo[7.3.0.0^3,7]dodeca-1,3⁽⁷⁾,8-triene

: 178557-13-6
4,10-dioxatricyclo[7.3.0.0^3,7]dodeca-1⁽⁹⁾,2,7-triene-2-carbaldehyde

Guidance literature:: 4,10-dioxatricyclo[7.3.0.0^3,7]dodeca-1,3⁽⁷⁾,8-triene; With tin(IV) chloride; In dichloromethane; for 0.0833333h; Inert atmosphere;

Dichloromethyl methyl ether; In dichloromethane; Inert atmosphere;
DOI:10.1016/j.bmcl.2017.02.053

Reference yield:

: 37142-37-3
1,4-Bis(2-chloroethoxy)benzene

: 178557-13-6
4,10-dioxatricyclo[7.3.0.0^3,7]dodeca-1⁽⁹⁾,2,7-triene-2-carbaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1: 92 percent / Fe, Br₂ / CCl₄ / 4.5 h / Ambient temperature

2: 80 percent / n-BuLi / tetrahydrofuran; hexane / 0.17 h

3: 71 percent / SnCl₄ / CH₂Cl₂ / 0.5 h

With n-butyllithium; bromine; tin(IV) chloride; iron; In tetrahydrofuran; tetrachloromethane; hexane; dichloromethane;
DOI:10.1021/jm960199j

Reference yield:

: 178557-12-5
1,4-bis(2-chloroethoxy)-2,5-dibromobenzene

: 178557-13-6
4,10-dioxatricyclo[7.3.0.0^3,7]dodeca-1⁽⁹⁾,2,7-triene-2-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / n-BuLi / tetrahydrofuran; hexane / 0.17 h

2: 71 percent / SnCl₄ / CH₂Cl₂ / 0.5 h

With n-butyllithium; tin(IV) chloride; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1021/jm960199j