(1S,2R)-3-(((S)-1-((methoxycarbonyl)oxy)-3-phenylpropan-2-yl)amino)-2-methyl-3-oxo-1-phenylpropyl acetate

Base Information

Chemical Name:(1S,2R)-3-(((S)-1-((methoxycarbonyl)oxy)-3-phenylpropan-2-yl)amino)-2-methyl-3-oxo-1-phenylpropyl acetate
CAS No.:1392205-86-5
Molecular Formula:C₂₃H₂₇NO₆
Molecular Weight:413.47
Hs Code.:

Synonyms:(1S,2R)-3-(((S)-1-((methoxycarbonyl)oxy)-3-phenylpropan-2-yl)amino)-2-methyl-3-oxo-1-phenylpropyl acetate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1S,2R)-3-(((S)-1-((methoxycarbonyl)oxy)-3-phenylpropan-2-yl)amino)-2-methyl-3-oxo-1-phenylpropyl acetate

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Technology Process of (1S,2R)-3-(((S)-1-((methoxycarbonyl)oxy)-3-phenylpropan-2-yl)amino)-2-methyl-3-oxo-1-phenylpropyl acetate

There total 2 articles about (1S,2R)-3-(((S)-1-((methoxycarbonyl)oxy)-3-phenylpropan-2-yl)amino)-2-methyl-3-oxo-1-phenylpropyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 67-56-1
methanol

: 1392205-83-2
(1S,2R)-3-((S)-4-benzyl-2-oxooxazolidin-3-yl)-2-methyl-3-oxo-1-phenylpropyl acetate

: 1392205-86-5
(1S,2R)-3-(((S)-1-((methoxycarbonyl)oxy)-3-phenylpropan-2-yl)amino)-2-methyl-3-oxo-1-phenylpropyl acetate

Guidance literature:: With C₁₇H₂₃BN₂O; at 25 ℃; for 26h; under 760.051 Torr; chemoselective reaction; Inert atmosphere;
DOI:10.1002/anie.201200304

Reference yield:

: (4S)-3-((3S,2R)-3-hydroxy-2-methyl-3-phenylpropanoyl)-4-benzyl-1,3-oxazolidin-2-one

: 1392205-86-5
(1S,2R)-3-(((S)-1-((methoxycarbonyl)oxy)-3-phenylpropan-2-yl)amino)-2-methyl-3-oxo-1-phenylpropyl acetate

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine; dmap / 20 h / 25 °C / Inert atmosphere

2: C₁₇H₂₃BN₂O / 26 h / 25 °C / 760.05 Torr / Inert atmosphere

With pyridine; dmap; C₁₇H₂₃BN₂O;
DOI:10.1002/anie.201200304