4-(4-carboxyphenylhydrazono)methyl-3-(4-methylphenyl)sydnone

Base Information

• Chemical Name: 4-(4-carboxyphenylhydrazono)methyl-3-(4-methylphenyl)sydnone
• CAS No.: 86870-31-7
• Molecular Formula: C₁₀H₈N₂O₃
• Molecular Weight: 204.185
• Mol file: 86870-31-7.mol

Synonyms:4-(4-carboxyphenylhydrazono)methyl-3-(4-methylphenyl)sydnone

Chemical Property of 4-(4-carboxyphenylhydrazono)methyl-3-(4-methylphenyl)sydnone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(4-carboxyphenylhydrazono)methyl-3-(4-methylphenyl)sydnone

There total 6 articles about 4-(4-carboxyphenylhydrazono)methyl-3-(4-methylphenyl)sydnone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

3-(4-methylphenyl)sydnone (3483-19-0) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 4-(4-carboxyphenylhydrazono)methyl-3-(4-methylphenyl)sydnone (86870-31-7)

Guidance literature:

With trichlorophosphate;

DOI:10.1002/hc.20210

Reference yield: 60.0%

3-(4-methylphenyl)sydnone (3483-19-0) + N-methyl-N-phenylformamide (93-61-8) → 4-(4-carboxyphenylhydrazono)methyl-3-(4-methylphenyl)sydnone (86870-31-7)

Guidance literature:

N-methyl-N-phenylformamide; With trichlorophosphate; for 0.5h;

3-(4-methylphenyl)sydnone; at 45 ℃;

With water; In acetone;

DOI:10.1016/j.ejmech.2012.06.011

Reference yield:

N-(p-tolyl)glycine (21911-69-3) → 4-(4-carboxyphenylhydrazono)methyl-3-(4-methylphenyl)sydnone (86870-31-7)

Guidance literature:

Multi-step reaction with 3 steps

1.1: hydrogenchloride; sodium nitrite / water / 2.5 h / 0 °C

2.1: acetic anhydride / Heating

3.1: trichlorophosphate / 0.5 h

3.2: 45 °C

With hydrogenchloride; acetic anhydride; sodium nitrite; trichlorophosphate; In water;

DOI:10.1016/j.ejmech.2012.06.011

upstream raw materials:

3-(4-methylphenyl)sydnone

N,N-dimethyl-formamide

N-methyl-N-phenylformamide

2-(nitroso(p-tolyl)amino)acetic acid

Downstream raw materials:

3-(4-methylphenyl)-4-formylsydnone thiosemicarbazone

1-piperidinomethyl-3-[1-(4-isobutylphenyl)ethyl]-4-[3-(ptolyl)-4-sydnonylidene]amino-1,2,4-triazol-5-thione

4-[4-(ethoxycarbonylphenylhydrazono)methyl-3-4-methylphenyl]sydnone

3-(4-methylphenyl)-formylsydnone-p-ethoxycarbonylbenzoyl-hydrazone