Technology Process of 1-(3-amino-4-hydroxy-6-methoxy-2-methyl-5-(3-phenylpropoxy)phenyl)ethanone
There total 8 articles about 1-(3-amino-4-hydroxy-6-methoxy-2-methyl-5-(3-phenylpropoxy)phenyl)ethanone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium 10% on activated carbon;
In
ethyl acetate;
at 20 ℃;
for 2h;
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: 0.5 h / 40 °C
2.1: titanium tetrachloride / dichloromethane / 0 - 20 °C
3.1: ammonium nitrate; trifluoroacetic anhydride / chloroform / 2 h / 0 °C
4.1: potassium carbonate / methanol / 3 h / 20 °C
4.2: pH 2
5.1: sodium hydride / N,N-dimethyl-formamide; oil / 0.25 h / 20 °C
5.2: 20 °C
6.1: lithium chloride / N,N-dimethyl-formamide / 3 h / 110 °C
7.1: hydrogen / palladium 10% on activated carbon / ethyl acetate / 2 h / 20 °C
With
ammonium nitrate; hydrogen; titanium tetrachloride; sodium hydride; potassium carbonate; trifluoroacetic anhydride; lithium chloride;
palladium 10% on activated carbon;
In
methanol; dichloromethane; chloroform; ethyl acetate; N,N-dimethyl-formamide; oil;
2.1: Friedel Crafts Acylation;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydride / N,N-dimethyl-formamide; oil / 0.25 h / 20 °C
1.2: 20 °C
2.1: lithium chloride / N,N-dimethyl-formamide / 3 h / 110 °C
3.1: hydrogen / palladium 10% on activated carbon / ethyl acetate / 2 h / 20 °C
With
hydrogen; sodium hydride; lithium chloride;
palladium 10% on activated carbon;
In
ethyl acetate; N,N-dimethyl-formamide; oil;
