Technology Process of 5,7-bis(benzyloxy)-6-iodo-3',4'-methylenedioxyisoflavone
There total 9 articles about 5,7-bis(benzyloxy)-6-iodo-3',4'-methylenedioxyisoflavone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hydroxide;
In
methanol; chloroform;
at 50 ℃;
for 0.0833333h;
microwave irradiation;
DOI:10.1016/j.tet.2006.06.066
- Guidance literature:
-
Multi-step reaction with 9 steps
1: 95 percent / H2 / Pd/C / methanol; ethyl acetate / 20 °C
2: 96 percent / I2; periodic acid / ethanol; H2O / 0.03 h / 45 °C / microwave irradiation
3: 82 percent / K2CO3 / dimethylformamide / 1 h / 70 °C
4: KOH / ethanol / 0.1 h / 88 °C / microwave irradiation
5: 4.15 g / aq. HCl / methanol; CHCl3 / 40 °C
6: 89 percent / pyridine / 0.1 h / 125 °C / microwave irradiation
7: [hydroxy(tosyloxy)iodo]benzene / CHCl3 / 0.2 h / 60 °C / microwave irradiation
8: 0.78 g / aq. NaOH / methanol; CHCl3 / 0.08 h / 50 °C / microwave irradiation
With
pyridine; hydrogenchloride; potassium hydroxide; sodium hydroxide; [hydroxy(tosyloxy)iodo]benzene; hydrogen; iodine; potassium carbonate; periodic acid;
palladium on activated charcoal;
In
methanol; ethanol; chloroform; water; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/j.tet.2006.06.066
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 95 percent / H2 / Pd/C / methanol; ethyl acetate / 20 °C
2: 96 percent / I2; periodic acid / ethanol; H2O / 0.03 h / 45 °C / microwave irradiation
3: 82 percent / K2CO3 / dimethylformamide / 1 h / 70 °C
4: KOH / ethanol / 0.1 h / 88 °C / microwave irradiation
5: 4.15 g / aq. HCl / methanol; CHCl3 / 40 °C
6: 89 percent / pyridine / 0.1 h / 125 °C / microwave irradiation
7: [hydroxy(tosyloxy)iodo]benzene / CHCl3 / 0.2 h / 60 °C / microwave irradiation
8: 0.78 g / aq. NaOH / methanol; CHCl3 / 0.08 h / 50 °C / microwave irradiation
With
pyridine; hydrogenchloride; potassium hydroxide; sodium hydroxide; [hydroxy(tosyloxy)iodo]benzene; hydrogen; iodine; potassium carbonate; periodic acid;
palladium on activated charcoal;
In
methanol; ethanol; chloroform; water; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/j.tet.2006.06.066
![1-[6-benzoyloxy-2,4-bis(benzyloxy)-3-iodophenyl]-2-(3,4-methylenedioxyphenyl)-3,3-dimethoxypropan-1-one](/Databaselist/images/loading.webp)
