3,5-BIS(3,5-DIMETHOXYBENZYLOXY)BENZYL BROMIDE

Base Information

• Chemical Name: 3,5-BIS(3,5-DIMETHOXYBENZYLOXY)BENZYL BROMIDE
• CAS No.: 176650-93-4
• Molecular Formula: C25H27 Br O6
• Molecular Weight: 503.39
• Hs Code.: 2909309090
• Mol file: 176650-93-4.mol

Synonyms:3,5-Bis[(3,5-dimethoxybenzyl)oxy]benzylbromide

Chemical Property of 3,5-BIS(3,5-DIMETHOXYBENZYLOXY)BENZYL BROMIDE

Chemical Property:

• Refractive Index: 1.58
• PSA: 55.38000
• LogP: 5.77390
• Storage Temp.: Refrigerator

Purity/Quality:

98%,99%, ^*data from raw suppliers

3,5-Bis(3,5-dimethoxybenzyloxy)benzyl Bromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R36/37/38:
• Hazard Codes: R36/37/38:
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,5-BIS(3,5-DIMETHOXYBENZYLOXY)BENZYL BROMIDE

There total 3 articles about 3,5-BIS(3,5-DIMETHOXYBENZYLOXY)BENZYL BROMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

3,5-bis(3,5-dimethoxybenzyloxy)benzyl alcohol (176650-92-3) → 3,5-bis(3,5-dimethoxybenzocarboxymethyl)benzyl bromide (176650-93-4)

Guidance literature:

With carbon tetrabromide; triphenylphosphine; Inert atmosphere; Schlenk technique;

DOI:10.1021/jo402428y

Reference yield:

3,5-dimethoxybenzyl alcohol (705-76-0) → 3,5-bis(3,5-dimethoxybenzocarboxymethyl)benzyl bromide (176650-93-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 61 percent / CBr₄, Ph₃P / tetrahydrofuran / 1 h

2: 1.) K₂CO₃, 18-crown-6-ether / 1.) acetone, reflux, 0.5 h, 2.) acetone, reflux, 42 h

3: 83 percent / CBr₄, Ph₃P / tetrahydrofuran / 2 h

With 18-crown-6 ether; carbon tetrabromide; potassium carbonate; triphenylphosphine; In tetrahydrofuran;

DOI:10.1021/ja954021i

Reference yield:

3,5-dimethoxybenzyl bromide (877-88-3) → 3,5-bis(3,5-dimethoxybenzocarboxymethyl)benzyl bromide (176650-93-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) K₂CO₃, 18-crown-6-ether / 1.) acetone, reflux, 0.5 h, 2.) acetone, reflux, 42 h

2: 83 percent / CBr₄, Ph₃P / tetrahydrofuran / 2 h

With 18-crown-6 ether; carbon tetrabromide; potassium carbonate; triphenylphosphine; In tetrahydrofuran;

DOI:10.1021/ja954021i

upstream raw materials:

3,5-bis(3,5-dimethoxybenzyloxy)benzyl alcohol

3,5-dimethoxybenzyl alcohol

3,5-dimethoxybenzyl bromide

Downstream raw materials:

bis-{3,5-bis[3,5-(dimethoxy)benzyloxy]benzyl}-dimethylammonium bromide

C₆₃H₆₂O₁₆

Refernces

• 1、 Fujimoto, Yuhei,Ubukata, Takashi,Yokoyama, Yasushi. "Dendrimer diarylethenes: The memory effect of conformation in polymer matrices". supporting information; experimental part. p. 5755 - 5757. Retrieved 2009/04/13.