3,5-BIS(3,5-DIMETHOXYBENZYLOXY)BENZYL ALCOHOL

Base Information

• Chemical Name: 3,5-BIS(3,5-DIMETHOXYBENZYLOXY)BENZYL ALCOHOL
• CAS No.: 176650-92-3
• Molecular Formula: C25H28 O7
• Molecular Weight: 440.493
• Hs Code.: 2909499000
• Mol file: 176650-92-3.mol

Synonyms:3,5-Bis(3,5-dimethoxybenzyloxy)benzylalc.

Chemical Property of 3,5-BIS(3,5-DIMETHOXYBENZYLOXY)BENZYL ALCOHOL

Chemical Property:

• Refractive Index: 1.575
• PSA: 75.61000
• LogP: 4.37130
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

3,5-Bis(3,5-dimethoxybenzyloxy)benzyl Alcohol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,5-BIS(3,5-DIMETHOXYBENZYLOXY)BENZYL ALCOHOL

There total 3 articles about 3,5-BIS(3,5-DIMETHOXYBENZYLOXY)BENZYL ALCOHOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

5-(hydroxymethyl)benzene-1,3-diol (29654-55-5) + 3,5-dimethoxybenzyl bromide (877-88-3) → 3,5-bis(3,5-dimethoxybenzyloxy)benzyl alcohol (176650-92-3)

Guidance literature:

With dibenzo-18-crown-6; potassium carbonate; In acetone; for 36h; Inert atmosphere; Reflux;

DOI:10.1039/b812503a

Reference yield:

3,5-dimethoxybenzyl alcohol (705-76-0) → 3,5-bis(3,5-dimethoxybenzyloxy)benzyl alcohol (176650-92-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 61 percent / CBr₄, Ph₃P / tetrahydrofuran / 1 h

2: 1.) K₂CO₃, 18-crown-6-ether / 1.) acetone, reflux, 0.5 h, 2.) acetone, reflux, 42 h

With 18-crown-6 ether; carbon tetrabromide; potassium carbonate; triphenylphosphine; In tetrahydrofuran;

DOI:10.1021/ja954021i

Reference yield:

3,5-dimethoxybenzyl alcohol (705-76-0) + 3,5-dimethoxybenzyl bromide (877-88-3) → 3,5-bis(3,5-dimethoxybenzyloxy)benzyl alcohol (176650-92-3)

Guidance literature:

With 18-crown-6 ether; potassium carbonate; Yield given. Multistep reaction; 1.) acetone, reflux, 0.5 h, 2.) acetone, reflux, 42 h;

DOI:10.1021/ja954021i

upstream raw materials:

3,5-dimethoxybenzyl alcohol

3,5-dimethoxybenzyl bromide

5-(hydroxymethyl)benzene-1,3-diol

Downstream raw materials:

C₂₈H₃₀O₇

C₅₇H₅₈O₁₅

C₅₈H₆₄N₂O₁₂

3,5-bis(3,5-dimethoxybenzocarboxymethyl)benzyl bromide