4,4,5,5-tetramethyl-2-[2,3,4-trimethoxy-6-(2-methoxy-ethoxymethoxymethyl)-phenyl]-[1,3,2]dioxaborolane

Base Information

• Chemical Name: 4,4,5,5-tetramethyl-2-[2,3,4-trimethoxy-6-(2-methoxy-ethoxymethoxymethyl)-phenyl]-[1,3,2]dioxaborolane
• CAS No.: 638164-12-2
• Molecular Formula: C₂₀H₃₃BO₈
• Molecular Weight: 412.288

Synonyms:4,4,5,5-tetramethyl-2-[2,3,4-trimethoxy-6-(2-methoxy-ethoxymethoxymethyl)-phenyl]-[1,3,2]dioxaborolane

Chemical Property of 4,4,5,5-tetramethyl-2-[2,3,4-trimethoxy-6-(2-methoxy-ethoxymethoxymethyl)-phenyl]-[1,3,2]dioxaborolane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,4,5,5-tetramethyl-2-[2,3,4-trimethoxy-6-(2-methoxy-ethoxymethoxymethyl)-phenyl]-[1,3,2]dioxaborolane

There total 2 articles about 4,4,5,5-tetramethyl-2-[2,3,4-trimethoxy-6-(2-methoxy-ethoxymethoxymethyl)-phenyl]-[1,3,2]dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) + 2-iodo-3,4,5-trimethoxy-1-(2-methoxy-ethoxymethoxymethyl)-benzene (638164-09-7) → 4,4,5,5-tetramethyl-2-[2,3,4-trimethoxy-6-(2-methoxy-ethoxymethoxymethyl)-phenyl]-[1,3,2]dioxaborolane (638164-12-2)

Guidance literature:

With triethylamine; CyJohnPhos; palladium diacetate; In 1,4-dioxane; at 80 ℃; for 0.5h;

DOI:10.1055/s-2003-42039

Reference yield:

2-iodo-3,4,5-trimethoxybenzyl alcohol (64490-45-5) → 4,4,5,5-tetramethyl-2-[2,3,4-trimethoxy-6-(2-methoxy-ethoxymethoxymethyl)-phenyl]-[1,3,2]dioxaborolane (638164-12-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 77 percent / iPr₂NEt / CH₂Cl₂ / 15 h / 0 - 25 °C

2: 84 percent / Et₃N; 2-(dicyclohexylphosphino)biphenyl / Pd(OAc)2 / dioxane / 0.5 h / 80 °C

With triethylamine; N-ethyl-N,N-diisopropylamine; CyJohnPhos; palladium diacetate; In 1,4-dioxane; dichloromethane;

DOI:10.1055/s-2003-42039

Reference yield:

(+/-)-α-methyl-2-iodo-4,5-methylenedioxybenzyl alcohol (64490-57-9) + 4,4,5,5-tetramethyl-2-[2,3,4-trimethoxy-6-(2-methoxy-ethoxymethoxymethyl)-phenyl]-[1,3,2]dioxaborolane (638164-12-2) → 1-{6-[2,3,4-trimethoxy-6-(2-methoxy-ethoxymethoxymethyl)-phenyl]-benzo[1,3]dioxol-5-yl}-ethanol (693219-96-4)

Guidance literature:

With barium dihydroxide; DavePhos; palladium diacetate; In 1,4-dioxane; water; at 100 ℃; for 1h;

DOI:10.1055/s-2003-42039

upstream raw materials:

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

2-iodo-3,4,5-trimethoxy-1-(2-methoxy-ethoxymethoxymethyl)-benzene

2-iodo-3,4,5-trimethoxybenzyl alcohol

Downstream raw materials:

1-{6-[2,3,4-trimethoxy-6-(2-methoxy-ethoxymethoxymethyl)-phenyl]-benzo[1,3]dioxol-5-yl}-ethanol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 638164-12-2 4,4,5,5-tetramethyl-2-[2,3,4-trimethoxy-6-(2-methoxy-ethoxymethoxymethyl)-phenyl]-[1,3,2]dioxaborolane

Send

Send

Metric Ton KG G Pound L ML

Send

Send