Technology Process of (+/-)-2-amino-4,4-bis(benzyloxymethyl)-1-cyclopentanol
There total 5 articles about (+/-)-2-amino-4,4-bis(benzyloxymethyl)-1-cyclopentanol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
triphenylphosphine;
In
tetrahydrofuran; water;
for 24h;
Heating;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) sodium hydride, 2.) tetrabutylammonium hydrogen sulfate / 1.) THF, 2 h, 2.) 4 h
2: 100 percent / m-chloroperbenzoic acid / CH2Cl2 / Ambient temperature
3: 95 percent / sodium azide, ammonium chloride / 2-ethoxy-ethanol; H2O / 18 h / Heating
4: 86 percent / triphenylphosphine / tetrahydrofuran; H2O / 24 h / Heating
With
sodium azide; ammonium chloride; tetra(n-butyl)ammonium hydrogensulfate; sodium hydride; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine;
In
tetrahydrofuran; 2-ethoxy-ethanol; dichloromethane; water;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) sodium hydride, 2.) tetrabutylammonium hydrogen sulfate / 1.) THF, 2 h, 2.) 4 h
2: 100 percent / m-chloroperbenzoic acid / CH2Cl2 / Ambient temperature
3: 95 percent / sodium azide, ammonium chloride / 2-ethoxy-ethanol; H2O / 18 h / Heating
4: 86 percent / triphenylphosphine / tetrahydrofuran; H2O / 24 h / Heating
With
sodium azide; ammonium chloride; tetra(n-butyl)ammonium hydrogensulfate; sodium hydride; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine;
In
tetrahydrofuran; 2-ethoxy-ethanol; dichloromethane; water;
