Technology Process of 2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-ol
There total 1 articles about 2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-ol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: piperidine / 4 h / 100 °C
2: potassium hydrogensulfate; dihydrogen peroxide / methanol / 20 °C
3: potassium hydroxide / 1 h / 20 °C
4: palladium 10% on activated carbon; hydrogen / ethanol; ethyl acetate / 5 h
With
piperidine; potassium hydrogensulfate; palladium 10% on activated carbon; hydrogen; dihydrogen peroxide; potassium hydroxide;
In
methanol; ethanol; ethyl acetate;
2: Baeyer-Villiger oxidation;
DOI:10.2174/157018010791526304
- Guidance literature:
-
Multi-step reaction with 2 steps
1: potassium carbonate; potassium iodide / acetonitrile / 60 - 80 °C
2: 1H-imidazole; iodine; triphenylphosphine / tetrahydrofuran / 5 h / 20 °C
With
1H-imidazole; iodine; potassium carbonate; triphenylphosphine; potassium iodide;
In
tetrahydrofuran; acetonitrile;
DOI:10.2174/157018010791526304
