diethyl 4-(2-phenylvinyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Base Information

• Chemical Name: diethyl 4-(2-phenylvinyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
• CAS No.: 1539-56-6
• Molecular Formula: C₂₁H₂₅NO₄
• Molecular Weight: 355.434
• Mol file: 1539-56-6.mol

Synonyms:diethyl 4-(2-phenylvinyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Chemical Property of diethyl 4-(2-phenylvinyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diethyl 4-(2-phenylvinyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

There total 5 articles about diethyl 4-(2-phenylvinyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

ethyl acetoacetate (141-97-9) + 3-phenyl-propenal (104-55-2) → diethyl 4-(2-phenylvinyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate (1539-56-6)

Guidance literature:

With ammonium acetate; In neat (no solvent); at 70 ℃; for 0.25h; Green chemistry;

DOI:10.1039/c3ra43601b

Reference yield: 95.0%

3-phenyl-propenal (104-55-2) + 3-Oxo-butaneperoxoic acid ethyl ester → diethyl 4-(2-phenylvinyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate (1539-56-6)

Guidance literature:

With ammonium acetate; In neat (no solvent); at 60 ℃; for 0.333333h;

DOI:10.1039/c3ta12476b

Reference yield: 80.0%

ammonium acetate (631-61-8,92206-38-7) + ethyl acetoacetate (141-97-9) + 3-phenyl-propenal (104-55-2) → diethyl 4-(2-phenylvinyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate (1539-56-6)

Guidance literature:

With Silica-sulphonic acid-[BMIM][PF₆]; In neat (no solvent); at 60 ℃; for 0.5h; Green chemistry;

DOI:10.1039/c4gc00923a

upstream raw materials:

ethyl acetoacetate

3-phenyl-propenal

urea

ammonium acetate

Downstream raw materials:

diethyl 2,6?dimethyl?4?cinnamylpyridine?3,5?dicarboxylate

diethyl 4-(2-phenylethenyl)-2,6-dimethyl-3,5-pyridinedicarboxylate

2,6-dimethyl-pyridine-3,5-dicarboxylic acid diethyl ester