tert-butyl (E)-4-<<6--3-<2-(ethoxycarbonyl)-1-propenyl>indol-1-yl>methyl>-3-methoxybenzoate

Base Information

• Chemical Name: tert-butyl (E)-4-<<6--3-<2-(ethoxycarbonyl)-1-propenyl>indol-1-yl>methyl>-3-methoxybenzoate
• CAS No.: 142535-42-0
• Molecular Formula: C₃₄H₄₂N₂O₆
• Molecular Weight: 574.717

Synonyms:tert-butyl (E)-4-<<6--3-<2-(ethoxycarbonyl)-1-propenyl>indol-1-yl>methyl>-3-methoxybenzoate

Chemical Property of tert-butyl (E)-4-<<6--3-<2-(ethoxycarbonyl)-1-propenyl>indol-1-yl>methyl>-3-methoxybenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl (E)-4-<<6--3-<2-(ethoxycarbonyl)-1-propenyl>indol-1-yl>methyl>-3-methoxybenzoate

There total 4 articles about tert-butyl (E)-4-<<6--3-<2-(ethoxycarbonyl)-1-propenyl>indol-1-yl>methyl>-3-methoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

tert-butyl 4-<<6--3-formylindol-1-yl>methyl>-3-methoxybenzoate (114085-91-5) + (carbethoxyethylidene)triphenylphosphorane (21382-82-1) → tert-butyl (E)-4-<<6--3-<2-(ethoxycarbonyl)-1-propenyl>indol-1-yl>methyl>-3-methoxybenzoate (142535-42-0)

Guidance literature:

In 1,4-dioxane;

Reference yield: 99.0%

[(1-ethoxycarbonyl)ethylidene]triphenylphosphorane (54356-04-6) + tert-butyl 4-<<6--3-formylindol-1-yl>methyl>-3-methoxybenzoate (114085-91-5) → tert-butyl (E)-4-<<6--3-<2-(ethoxycarbonyl)-1-propenyl>indol-1-yl>methyl>-3-methoxybenzoate (142535-42-0)

Guidance literature:

In 1,4-dioxane; for 18h; Heating;

DOI:10.1021/jm00091a010

Reference yield:

t-butyl 4-bromomethyl-3-methoxybenzoate (104436-91-1) → tert-butyl (E)-4-<<6--3-<2-(ethoxycarbonyl)-1-propenyl>indol-1-yl>methyl>-3-methoxybenzoate (142535-42-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 71 percent / K₂CO₃ / dimethylformamide / 48 h

2: 99 percent / dioxane / 18 h / Heating

With potassium carbonate; In 1,4-dioxane; N,N-dimethyl-formamide;

DOI:10.1021/jm00091a010

upstream raw materials:

[(1-ethoxycarbonyl)ethylidene]triphenylphosphorane

tert-butyl 4-<<6--3-formylindol-1-yl>methyl>-3-methoxybenzoate

t-butyl 4-bromomethyl-3-methoxybenzoate

6--3-formylindole

Downstream raw materials:

N-[4-[6-(N-Cyclopentylmethylcarbamoyl)-3-[2-(N,N-dimethylcarbamoyl)propyl]indol-1-ylmethyl]-3-methoxybenzoyl]-2-methylbenzenesulphonamide

tert-butyl 4-<<6--3-<2-(N,N-dimethylcarbamoyl)propyl>indol-1-yl>methyl>-3-methoxybenzoate

tert-butyl 4-<<6--3-(2-carboxypropyl)indol-1-yl>methyl>-3-methoxybenzoate

4-[6-(N-cyclopentylmethylcarbamoyl)-3-[2-(N,N-dimethylcarbamoyl)propyl]-indol-1-ylmethyl]-3-methoxybenzoic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 142535-42-0 tert-butyl (E)-4-<<6--3-<2-(ethoxycarbonyl)-1-propenyl>indol-1-yl>methyl>-3-methoxybenzoate

Send

Send

Metric Ton KG G Pound L ML

Send

Send