2-(benzyloxy)-5-bromo-4-methylpyridine

Base Information

• Chemical Name: 2-(benzyloxy)-5-bromo-4-methylpyridine
• CAS No.: 847349-87-5
• Molecular Formula: C₁₃H₁₂BrNO
• Molecular Weight: 278.148
• Mol file: 847349-87-5.mol

Synonyms:2-(benzyloxy)-5-bromo-4-methylpyridine

Chemical Property of 2-(benzyloxy)-5-bromo-4-methylpyridine

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

2-(Benzyloxy)-5-bromo-4-picoline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(benzyloxy)-5-bromo-4-methylpyridine

There total 3 articles about 2-(benzyloxy)-5-bromo-4-methylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

→ 2-(benzyloxy)-5-bromo-4-methylpyridine (847349-87-5)

Guidance literature:

Reference yield: 93.0%

5-bromo-4-methylpyridin-2(1H)-one (164513-38-6) + benzyl bromide (100-39-0) → 2-(benzyloxy)-5-bromo-4-methylpyridine (847349-87-5)

Guidance literature:

With silver carbonate; In benzene; at 20 ℃; for 96h;

DOI:10.1016/j.bmc.2009.05.069

Reference yield: 64.0%

benzyl alcohol (100-51-6,185532-71-2) + 5-bromo-2-chloro-4-methylpyridine (778611-64-6) → 2-(benzyloxy)-5-bromo-4-methylpyridine (847349-87-5)

Guidance literature:

benzyl alcohol; With sodium hydride; In tetrahydrofuran; mineral oil; at 20 ℃; for 0.25h;

5-bromo-2-chloro-4-methylpyridine; In tetrahydrofuran; mineral oil; Reflux;

upstream raw materials:

5-bromo-4-methylpyridin-2(1H)-one

benzyl bromide

benzyl alcohol

5-bromo-2-chloro-4-methylpyridine

Downstream raw materials:

n-propyl 6-(benzyloxy)-4-methylpyridine-3-carboxylate