2-ethoxy-propyl p-tolyl sulphone

Base Information

• Chemical Name: 2-ethoxy-propyl p-tolyl sulphone
• CAS No.: 91765-54-7
• Molecular Formula: C₁₂H₁₈O₃S
• Molecular Weight: 242.339
• Mol file: 91765-54-7.mol

Synonyms:2-ethoxy-propyl p-tolyl sulphone

Chemical Property of 2-ethoxy-propyl p-tolyl sulphone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-ethoxy-propyl p-tolyl sulphone

There total 5 articles about 2-ethoxy-propyl p-tolyl sulphone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

ethyl-(3-p-tolylsulphonylpropyl)-p-tolylsulphonium benzenesulphonate (82777-30-8) → ethyl p-tolyl sulfide (622-63-9) + 2-ethoxy-propyl p-tolyl sulphone (91765-54-7)

Guidance literature:

With sodium ethanolate; In ethanol; at 25 ℃; for 48h;

DOI:10.1039/P29820000579

Reference yield:

3-bromopropyl p-tolyl sulphone (5755-77-1) → 2-ethoxy-propyl p-tolyl sulphone (91765-54-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 87 percent / 0.12 M sodium ethoxide / ethanol / 1 h / 80 °C

2: 1) dichloromethane, 4 h; ether, 0 deg C; 2) chloroform, 12 h

3: 91 percent / 0.152 M sodium ethoxide / ethanol / 48 h / 25 °C

With sodium ethanolate; In ethanol;

DOI:10.1039/P29820000579

Reference yield:

C17H20O2S2 (82777-28-4) → 2-ethoxy-propyl p-tolyl sulphone (91765-54-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) dichloromethane, 4 h; ether, 0 deg C; 2) chloroform, 12 h

2: 91 percent / 0.152 M sodium ethoxide / ethanol / 48 h / 25 °C

With sodium ethanolate; In ethanol;

DOI:10.1039/P29820000579

upstream raw materials:

ethyl-(3-p-tolylsulphonylpropyl)-p-tolylsulphonium benzenesulphonate

ethanol

4-methylphenyl prop-1-enyl sulfone

1,2-Bis(4-methylphenylsulfonyl)propane

Downstream raw materials:

1-(4-methylphenylsulfonyl)propan-2-ol

4-toluenesulfonylacetone