3,3'-dibromo-5,5'-dicarboxy-4,4'-dihydroxydiphenylmethane

Base Information

• Chemical Name: 3,3'-dibromo-5,5'-dicarboxy-4,4'-dihydroxydiphenylmethane
• CAS No.: 130883-74-8
• Molecular Formula: C₁₅H₁₀Br₂O₆
• Molecular Weight: 446.049
• Mol file: 130883-74-8.mol

Synonyms:3,3'-dibromo-5,5'-dicarboxy-4,4'-dihydroxydiphenylmethane

Chemical Property of 3,3'-dibromo-5,5'-dicarboxy-4,4'-dihydroxydiphenylmethane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,3'-dibromo-5,5'-dicarboxy-4,4'-dihydroxydiphenylmethane

There total 3 articles about 3,3'-dibromo-5,5'-dicarboxy-4,4'-dihydroxydiphenylmethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 3-bromosalicylic acid (3883-95-2) → 3,3'-dibromo-5,5'-dicarboxy-4,4'-dihydroxydiphenylmethane (130883-74-8)

Guidance literature:

With sulfuric acid; In methanol; water; for 14h; Ambient temperature;

DOI:10.1021/jm00105a053

Reference yield:

C17H14O6Br2 (942296-83-5) → 3,3'-dibromo-5,5'-dicarboxy-4,4'-dihydroxydiphenylmethane (130883-74-8)

Guidance literature:

With sodium hydroxide; In 1,4-dioxane; at 80 ℃;

DOI:10.1016/j.bmcl.2007.02.069

Reference yield:

methyl 3-bromo-2-hydroxybenzoate (28165-45-9) → 3,3'-dibromo-5,5'-dicarboxy-4,4'-dihydroxydiphenylmethane (130883-74-8)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂SO₄; acetic acid / 95 °C

2: aq. NaOH / dioxane / 80 °C

With sodium hydroxide; sulfuric acid; acetic acid; In 1,4-dioxane;

DOI:10.1016/j.bmcl.2007.02.069

upstream raw materials:

formaldehyd

3-bromosalicylic acid

C₁₇H₁₄O₆Br₂

methyl 3-bromo-2-hydroxybenzoate

Downstream raw materials:

methyl-3-bromo-5-(1-(5-bromo-4-methoxy-3-(methoxycarbonyl)phenyl)hept-1-enyl)-2-methoxybenzoate

[3',3''-dibromo-4',4''-dimethoxy-5',5''-di(methoxycarbonyl)diphenyl]methanone

3,3'-dibromo-4,4'-dimethoxy-5,5'-bis(methoxycarbonyl)diphenylmethane