3883-95-2

Basic information

• Product Name: 3-BROMO-2-HYDROXYBENZOIC ACID
• Synonyms: 3-BROMOSALICYLIC ACID;3-BROMO-2-HYDROXYBENZOIC ACID;AURORA KA-2536;Zinc02507163;Benzoic acid,3-broMo-2-hydroxy-
• CAS NO: 3883-95-2
• Molecular Formula: C₇H₅BrO₃
• Molecular Weight: 217.0168
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 3883-95-2.mol

Chemical Properties

• Melting Point: 219-220 °C
• Boiling Point: 301.4 °C at 760 mmHg
• Flash Point: 136.1 °C
• Appearance: /
• Density: 1.861 g/cm³
• Vapor Pressure: 0.000469mmHg at 25°C
• Refractive Index: 1.654
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility: Methanol, DMSO
• PKA: 2.43±0.10(Predicted)
• CAS DataBase Reference: 3-BROMO-2-HYDROXYBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-2-HYDROXYBENZOIC ACID(3883-95-2)
• EPA Substance Registry System: 3-BROMO-2-HYDROXYBENZOIC ACID(3883-95-2)

Safety Data

• Hazardous Substances Data: 3883-95-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-BROMO-2-HYDROXYBENZOIC ACID is used as an intermediate in the synthesis of various pharmaceutical compounds. Specifically, it is a potential intermediate in the production of 3-[4-(2-Pyridylsulfamoyl)phenyl] Sulfasalazine (P995810), which is an impurity of Sulfasalazine (S699084). Sulfasalazine is an anti-inflammatory drug used in the treatment of gastrointestinal conditions, particularly granulomatous colitis.

InChI:InChI=1/C7H5BrO3/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3,9H,(H,10,11)

Upstream product

• 56-23-5 tetrachloromethane 
• 95-56-7 2-hydroxybromobenzene 
• 871883-47-5 8-bromo-2,3-dimethyl-chromen-4-one 
• 7647-01-0 hydrogenchloride 
• 28165-47-1 3-bromo-2-hydroxybenzamide 
• 101084-39-3 2-methoxy-3-bromobenzoic acid 
• 1333434-76-6 2-bromophenyl tert-butyl carbonate 
• 69-72-7 salicylic acid 
• 108-93-0 cyclohexanol 
• 108-94-1 cyclohexanone 
• 57688-24-1 3-bromo-2-hydroxy-5-nitro-benzoic acid 
• 831-51-6 3-amino-5-nitrosalicylic acid 
• 608-33-3 2,6-dibromophenol 
• 854914-90-2 3-bromo-2-hydroxy-thiobenzoic acid S-methyl ester 

Downstream Products

• 95-56-7 2-hydroxybromobenzene 
• 260806-90-4 methyl 3-bromo-2-methoxybenzoate 
• 1879887-94-1 2-morpholino-8-(naphthalen-1-yl)-4H-1,3-benzoxazin-4-one 
• 30762-15-3 3-hexylsalicylic acid 
• 885270-74-6 8-bromo-2H-chromene-3-carboxylic acid 
• 267651-23-0 1-(3-bromo-2-methoxyphenyl)ethan-1-one 

Relevant articles and documents

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