Malonic acid (Z)-1-benzyloxy-5-phenylsulfanyl-pent-3-enyl ester ethyl ester

Base Information

• Chemical Name: Malonic acid (Z)-1-benzyloxy-5-phenylsulfanyl-pent-3-enyl ester ethyl ester
• CAS No.: 128669-74-9
• Molecular Formula: C₂₃H₂₆O₅S
• Molecular Weight: 414.522
• Mol file: 128669-74-9.mol

Synonyms:Malonic acid (Z)-1-benzyloxy-5-phenylsulfanyl-pent-3-enyl ester ethyl ester

Chemical Property of Malonic acid (Z)-1-benzyloxy-5-phenylsulfanyl-pent-3-enyl ester ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Malonic acid (Z)-1-benzyloxy-5-phenylsulfanyl-pent-3-enyl ester ethyl ester

There total 4 articles about Malonic acid (Z)-1-benzyloxy-5-phenylsulfanyl-pent-3-enyl ester ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

Malonic acid 1-benzyloxy-5-phenylsulfanyl-pent-3-ynyl ester ethyl ester (128669-71-6) → Malonic acid (Z)-1-benzyloxy-5-phenylsulfanyl-pent-3-enyl ester ethyl ester (128669-74-9)

Guidance literature:

With hydrogen; palladium on barium sulfate; In methanol;

DOI:10.1039/c39900000418

Reference yield:

C9H7LiS → Malonic acid (Z)-1-benzyloxy-5-phenylsulfanyl-pent-3-enyl ester ethyl ester (128669-74-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 2.) BF₃*Et₂O / 1.) THF, -78 deg C

2: 90 percent / dicyclohexylcarbodiimide, 4-N,N-dimethylaminopyridine / CH₂Cl₂ / Ambient temperature

3: 81 percent / H₂ / 5percent Pd-BaSO₄ / methanol

With dmap; boron trifluoride diethyl etherate; hydrogen; dicyclohexyl-carbodiimide; palladium on barium sulfate; In methanol; dichloromethane;

DOI:10.1039/c39900000418

Reference yield:

benzylglycidyl ether (70278-02-3) → Malonic acid (Z)-1-benzyloxy-5-phenylsulfanyl-pent-3-enyl ester ethyl ester (128669-74-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 2.) BF₃*Et₂O / 1.) THF, -78 deg C

2: 90 percent / dicyclohexylcarbodiimide, 4-N,N-dimethylaminopyridine / CH₂Cl₂ / Ambient temperature

3: 81 percent / H₂ / 5percent Pd-BaSO₄ / methanol

With dmap; boron trifluoride diethyl etherate; hydrogen; dicyclohexyl-carbodiimide; palladium on barium sulfate; In methanol; dichloromethane;

DOI:10.1039/c39900000418

upstream raw materials:

Malonic acid 1-benzyloxy-5-phenylsulfanyl-pent-3-ynyl ester ethyl ester

benzylglycidyl ether

1-Benzyloxy-5-phenylsulfanyl-pent-3-yn-1-ol

Downstream raw materials:

(3S,4S,6S)-6-Benzyloxy-2-oxo-3-phenylsulfanyl-4-vinyl-tetrahydro-pyran-3-carboxylic acid ethyl ester

(3S,4S,6R)-6-Benzyloxy-2-oxo-3-phenylsulfanyl-4-vinyl-tetrahydro-pyran-3-carboxylic acid ethyl ester

2-Diazo-malonic acid (Z)-1-benzyloxy-5-phenylsulfanyl-pent-3-enyl ester ethyl ester