4-Chloro-1,3-Dimethyl-1H-Pyrazolo[3,4-B]Pyridine-5-Carbonyl Chloride

Base Information

Chemical Name:4-Chloro-1,3-Dimethyl-1H-Pyrazolo[3,4-B]Pyridine-5-Carbonyl Chloride
CAS No.:175201-95-3
Molecular Formula:C9H7 Cl2 N3 O
Molecular Weight:244.08
Hs Code.:29331990
European Community (EC) Number:673-092-9
DSSTox Substance ID:DTXSID70370909
Wikidata:Q82158088
Mol file:175201-95-3.mol

Synonyms:175201-95-3;4-Chloro-1,3-Dimethyl-1H-Pyrazolo[3,4-B]Pyridine-5-Carbonyl Chloride;4-chloro-1,3-dimethylpyrazolo[3,4-b]pyridine-5-carbonyl chloride;4-CHLORO-1,3-DIMETHYL-1H-PYRAZOL[3,4-B]PYRIDINE-5-CARBONYL CHLORIDE;SCHEMBL4772965;DTXSID70370909;STR04673;MFCD00067960;AKOS025117189;FT-0617974;F81387;4-Chloro-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carbonylchloride;4-CHLORO-1,3-DIMETHYLPYRAZOLO-[3,4-B]PYRIDINE-5-CARBONYL CHLORIDE

Suppliers and Price of 4-Chloro-1,3-Dimethyl-1H-Pyrazolo[3,4-B]Pyridine-5-Carbonyl Chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
4-Chloro-1,3-dimethylpyrazolo[3,4-b]pyridine-5-carbonyl chloride
500 mg
$ 128.00

SynQuest Laboratories
4-Chloro-1,3-dimethylpyrazolo[3,4-b]pyridine-5-carbonyl chloride
1 g
$ 200.00

Frontier Specialty Chemicals
4-Chloro-1,3-dimethylpyrazolo[3,4-b]pyridine-5-carbonylchloride 97%
1g
$ 250.00

Chemenu
4-Chloro-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carbonylchloride 97%
5g
$ 533.00

Apolloscientific
4-Chloro-1,3-dimethylpyrazolo[3,4-b]pyridine-5-carbonylchloride
1g
$ 182.00

Apolloscientific
4-Chloro-1,3-dimethylpyrazolo[3,4-b]pyridine-5-carbonylchloride
500mg
$ 116.00

American Custom Chemicals Corporation
4-CHLORO-1,3-DIMETHYLPYRAZOLO[3,4-B]PYRIDINE-5-CARBONYL CHLORIDE 95.00%
1G
$ 759.41

American Custom Chemicals Corporation
4-CHLORO-1,3-DIMETHYLPYRAZOLO[3,4-B]PYRIDINE-5-CARBONYL CHLORIDE 95.00%
500MG
$ 693.92

Total 5 raw suppliers

Chemical Property of 4-Chloro-1,3-Dimethyl-1H-Pyrazolo[3,4-B]Pyridine-5-Carbonyl Chloride

Chemical Property:

Vapor Pressure:1.61E-05mmHg at 25°C
Melting Point:106℃
Refractive Index:1.682
Boiling Point:365.1°Cat760mmHg
Flash Point:174.6°C
PSA：47.78000
Density:1.57g/cm³
LogP:2.30910
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:242.9966172
Heavy Atom Count:15
Complexity:276

Purity/Quality:

98% ^*data from raw suppliers

4-Chloro-1,3-dimethylpyrazolo[3,4-b]pyridine-5-carbonyl chloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:C
Statements: 34
Safety Statements: 26-36/37/39-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NN(C2=NC=C(C(=C12)Cl)C(=O)Cl)C

Technology Process of 4-Chloro-1,3-Dimethyl-1H-Pyrazolo[3,4-B]Pyridine-5-Carbonyl Chloride

There total 4 articles about 4-Chloro-1,3-Dimethyl-1H-Pyrazolo[3,4-B]Pyridine-5-Carbonyl Chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 175201-94-2
4-chloro-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid

: 175201-95-3
4-Chloro-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carbonyl chloride

Guidance literature:: With thionyl chloride; at 80 ℃;
DOI:10.1016/j.bmcl.2003.10.025

Reference yield:

: 3524-32-1
5-Amino-1,3-dimethylpyrazole

: 175201-95-3
4-Chloro-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carbonyl chloride

Guidance literature:: Multi-step reaction with 4 steps

1: 89 percent / 1 h / 120 °C

2: 77 percent / POCl₃ / 18 h / 120 °C

3: 99 percent / potassium hydroxide / H₂O; 1,2-dimethoxy-ethane / 18 h / 20 °C

4: SOCl₂ / 1 h / 80 °C

With potassium hydroxide; thionyl chloride; trichlorophosphate; In 1,2-dimethoxyethane; water;
DOI:10.1016/j.bmc.2004.05.032

Reference yield:

: 20481-15-6
ethyl 4-chloro-1,3-dimethylpyrazolo[3,4-b]pyridine-5-carboxylate

: 175201-95-3
4-Chloro-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carbonyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / potassium hydroxide / H₂O; 1,2-dimethoxy-ethane / 18 h / 20 °C

2: SOCl₂ / 1 h / 80 °C

With potassium hydroxide; thionyl chloride; In 1,2-dimethoxyethane; water;
DOI:10.1016/j.bmc.2004.05.032