{3-[1-(3-Dimethylamino-phenyl)-ethyl]-phenyl}-phenyl-methanone

Base Information

• Chemical Name: {3-[1-(3-Dimethylamino-phenyl)-ethyl]-phenyl}-phenyl-methanone
• CAS No.: 98509-09-2
• Molecular Formula: C₂₃H₂₃NO
• Molecular Weight: 329.442
• Mol file: 98509-09-2.mol

Synonyms:{3-[1-(3-Dimethylamino-phenyl)-ethyl]-phenyl}-phenyl-methanone

Chemical Property of {3-[1-(3-Dimethylamino-phenyl)-ethyl]-phenyl}-phenyl-methanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of {3-[1-(3-Dimethylamino-phenyl)-ethyl]-phenyl}-phenyl-methanone

There total 6 articles about {3-[1-(3-Dimethylamino-phenyl)-ethyl]-phenyl}-phenyl-methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(3-{1-[3-(Imino-phenyl-methyl)-phenyl]-ethyl}-phenyl)-dimethyl-amine → {3-[1-(3-Dimethylamino-phenyl)-ethyl]-phenyl}-phenyl-methanone (98509-09-2)

Guidance literature:

With hydrogenchloride; In water; Yield given;

DOI:10.1021/ja00309a004

Reference yield:

3-bromo-N,N-dimethylaniline (16518-62-0) → {3-[1-(3-Dimethylamino-phenyl)-ethyl]-phenyl}-phenyl-methanone (98509-09-2)

Guidance literature:

Multi-step reaction with 4 steps

1: 1.) butyllithium / 1.) diethyl ether, hexane, 0 deg C; 2.) 0 deg C, 1 h

2: NaBH₄, CF₃COOH / CH₂Cl₂ / 2 h

3: 1.) n-BuLi / 1.) diethyl ether, 0 deg C, 30 min; 2.) diethyl ether, 1 h

4: HCl / H₂O

With hydrogenchloride; sodium tetrahydroborate; n-butyllithium; trifluoroacetic acid; In dichloromethane; water;

DOI:10.1021/ja00309a004

Reference yield:

benzonitrile (100-47-0) → {3-[1-(3-Dimethylamino-phenyl)-ethyl]-phenyl}-phenyl-methanone (98509-09-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) n-BuLi / 1.) diethyl ether, 0 deg C, 30 min; 2.) diethyl ether, 1 h

2: HCl / H₂O

With hydrogenchloride; n-butyllithium; In water;

DOI:10.1021/ja00309a004

upstream raw materials:

3-bromo-N,N-dimethylaniline

benzonitrile

1-(3-Bromophenyl)ethanone

3-bromophenyl-3'-dimethylaminophenylethane

Downstream raw materials:

hydroxy-diphenyl-methyl

benzophenone anion