(+/-)-3-phenyl-cyclopropane-1r,2t-dicarboxylic acid dimethyl ester

Base Information

• Chemical Name: (+/-)-3-phenyl-cyclopropane-1r,2t-dicarboxylic acid dimethyl ester
• CAS No.: 20098-66-2
• Molecular Formula: C₁₃H₁₄O₄
• Molecular Weight: 234.252
• Mol file: 20098-66-2.mol

Synonyms:(+/-)-3-phenyl-cyclopropane-1r,2t-dicarboxylic acid dimethyl ester

Chemical Property of (+/-)-3-phenyl-cyclopropane-1r,2t-dicarboxylic acid dimethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-3-phenyl-cyclopropane-1r,2t-dicarboxylic acid dimethyl ester

There total 18 articles about (+/-)-3-phenyl-cyclopropane-1r,2t-dicarboxylic acid dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

methanol (67-56-1) + (1RS,2RS,3RS)-3-Phenylcyclopropane-1,2-dicarboxylic acid (19952-66-0) → (+/-)-3-phenyl-cyclopropane-1r,2t-dicarboxylic acid dimethyl ester (20098-66-2)

Guidance literature:

sulfuric acid;

DOI:10.1002/hlca.19910740832

Reference yield: 30.0%

Methyl cinnamate (103-26-4,1754-62-7) + methyl chloroacetate (96-34-4) → t-3-Phenyl-r-1,c-2-cyclopropandicarbonsaeure-dimethylester (19952-65-9) + (+/-)-3-phenyl-cyclopropane-1r,2t-dicarboxylic acid dimethyl ester (20098-66-2)

Guidance literature:

With methanol; sodium hydride; In toluene; paraffin; at 50 - 70 ℃; for 12h;

Reference yield: 25.0%

benzylidene dichloride (98-87-3) + dimethylfumarate (624-49-7) → (+/-)-3-phenyl-cyclopropane-1r,2t-dicarboxylic acid dimethyl ester (20098-66-2)

Guidance literature:

With tetrabutylammomium bromide; tetra-(n-butyl)ammonium iodide; In N,N-dimethyl-formamide; Ambient temperature; electrolysis;

DOI:10.1016/S0040-4020(98)00059-3

upstream raw materials:

diazomethane

(1RS,2RS,3RS)-3-Phenylcyclopropane-1,2-dicarboxylic acid

(+/-)-5c-phenyl-4,5-dihydro-1H-pyrazole-3,4r-dicarboxylic acid dimethyl ester

(+/-)-5t-phenyl-4,5-dihydro-1H-pyrazole-3,4r-dicarboxylic acid dimethyl ester

Downstream raw materials:

(1RS,2RS,3RS)-3-Phenylcyclopropane-1,2-dicarboxylic acid

C₁₁H₈O₄^(2-)*2K⁽¹⁺⁾

C₁₁H₁₄N₄O₂