Technology Process of 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluorooctanedioic acid (4-cyanophenyl)amide hydroxyamide
There total 4 articles about 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluorooctanedioic acid (4-cyanophenyl)amide hydroxyamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
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1308677-07-7
benzyl 7-(4-cyanophenylcarbamoyl)-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptanoate
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1308677-32-8
2,2,3,3,4,4,5,5,6,6,7,7-dodecafluorooctanedioic acid (4-cyanophenyl)amide hydroxyamide
- Guidance literature:
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With
hydroxylamine;
In
tetrahydrofuran;
at 20 ℃;
for 24h;
Inert atmosphere;
DOI:10.1016/j.bmc.2011.11.041
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-
678-45-5
2,2,3,3,4,4,5,5,6,6,7,7-dodecafluorooctanedioic acid
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1308677-32-8
2,2,3,3,4,4,5,5,6,6,7,7-dodecafluorooctanedioic acid (4-cyanophenyl)amide hydroxyamide
- Guidance literature:
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Multi-step reaction with 4 steps
1: thionyl chloride; N,N-dimethyl-formamide / 4 h / Inert atmosphere; Reflux
2: 2 h / 100 °C / Inert atmosphere; Cooling with ice
3: triethylamine / tetrahydrofuran / 5 h / 20 °C / Inert atmosphere; Cooling with ice
4: hydroxylamine / tetrahydrofuran / 24 h / 20 °C / Inert atmosphere
With
thionyl chloride; hydroxylamine; triethylamine; N,N-dimethyl-formamide;
In
tetrahydrofuran;
DOI:10.1016/j.bmc.2011.11.041
-
-
1308677-32-8
2,2,3,3,4,4,5,5,6,6,7,7-dodecafluorooctanedioic acid (4-cyanophenyl)amide hydroxyamide
- Guidance literature:
-
With
hydroxylamine hydrochloride; triethylamine;
In
tetrahydrofuran;
at 20 ℃;
for 24h;
DOI:10.1016/j.bmcl.2017.02.050
