(E)-3-(4-ACETYL-PHENYL)-ACRYLIC ACID BUTYL ESTER

Base Information

• Chemical Name: (E)-3-(4-ACETYL-PHENYL)-ACRYLIC ACID BUTYL ESTER
• CAS No.: 173464-57-8
• Molecular Formula: C15H18 O3
• Molecular Weight: 246.306
• Mol file: 173464-57-8.mol

Synonyms:2-Propenoicacid, 3-(4-acetylphenyl)-, butyl ester, (E)-;(2E)-3-(4-Acetylphenyl)-2-propenoic acid butyl ester; (E)-Butyl4-acetylcinnamate; Butyl (E)-3-(4-acetylphenyl)-2-propenoate; Butyltrans-4-acetylcinnamate

Chemical Property of (E)-3-(4-ACETYL-PHENYL)-ACRYLIC ACID BUTYL ESTER

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.539
• Boiling Point: 386.387°C at 760 mmHg
• Flash Point: 170.264°C
• PSA: 43.37000
• Density: 1.064g/cm³
• LogP: 3.24570

Purity/Quality:

99%min ^*data from raw suppliers

(E)-3-(4-ACETYL-PHENYL)-ACRYLIC ACID BUTYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (E)-3-(4-ACETYL-PHENYL)-ACRYLIC ACID BUTYL ESTER

There total 48 articles about (E)-3-(4-ACETYL-PHENYL)-ACRYLIC ACID BUTYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-bromo-4-methoxy-benzene (104-92-7) + acrylic acid n-butyl ester (141-32-2,9003-49-0) → (E)-3-(4-methoxyphenyl)acrylic acid butyl ester (173464-57-8,40458-52-4,121725-19-7)

Guidance literature:

With 1,2-bis(diphenylphosphino)-1'-(diisopropylphosphino)-3',4-di-tert-butyl ferrocene; potassium carbonate; bis(η3-allyl-μ-chloropalladium(II)); In N,N-dimethyl-formamide; at 130 ℃; for 20h;

DOI:10.1016/j.tet.2005.06.065

Reference yield: 100.0%

acrylic acid n-butyl ester (141-32-2,9003-49-0) + 4-Iodoacetophenone (13329-40-3) → (E)-3-(4-acetylphenyl)acrylic acid butyl ester (173464-57-8)

Guidance literature:

With C₂₉H₃₃Cl₂N₅Pd; tetrabutylammomium bromide; sodium carbonate; In N,N-dimethyl acetamide; at 140 ℃; for 3h; Inert atmosphere;

DOI:10.1021/om100890q

Reference yield: 100.0%

acrylic acid n-butyl ester (141-32-2,9003-49-0) + para-bromoacetophenone (99-90-1) → (E)-3-(4-acetylphenyl)acrylic acid butyl ester (173464-57-8)

Guidance literature:

With palladium diacetate; caesium carbonate; In N,N-dimethyl acetamide; at 100 ℃; for 3h; Further Variations:; Reagents; Product distribution;

DOI:10.1016/j.jorganchem.2007.11.015

upstream raw materials:

acrylic acid n-butyl ester

4-methoxy-benzoyl chloride

4-methoxy-phenyl-sulphonyl chloride

1-bromo-4-methoxy-benzene

Refernces

• 1、 Priyadarshani, Nilusha,Suriboot, Jakkrit,Bergbreiter, David E.. "Recycling Pd colloidal catalysts using polymeric phosphine ligands and polyethylene as a solvent". . p. 1361 - 1367. Retrieved 2013.
• 2、 Broadwater, Steven J.,McQuade, D. Tyler. "Investigating PdEnCat catalysis". . p. 2131 - 2134. Retrieved 2006.
• 3、 Borja, Guadalupe,Monge-Marcet, Amalia,Pleixats, Roser,Parella, Teodor,Cattoen, Xavier,Wong Chi Man, Michel. "Recyclable hybrid silica-based catalysts derived from Pd-NHC complexes for suzuki, heck and sonogashira reactions". . p. 3625 - 3635. Retrieved 2012.
• 4、 Yang, Yanfei,Priyadarshani, Nilusha,Khamatnurova, Tatyana,Suriboot, Jakkrit,Bergbreiter, David E.. "Polyethylene as a nonvolatile solid cosolvent phase for catalyst separation and recovery". . p. 14714 - 14717,4. Retrieved 2012.
• 5、 Babaee, Heshmatollah,Javad Sabounchei, Seyyed,Naghipour, Ali,Notash, Behrouz,Sayadi, Mohsen,Sedghi, Asieh. "A comparative study of palladium-based coordination compounds with bidentate (N,N, P,P and P,O) ligands; Design, synthesis, X-ray structural, catalytic activity and DFT studies". . . Retrieved 2020/10/13.
• 6、 Swart, Marthinus R.,Twigge, Linette,Erasmus, Elizabeth,Marais, Charlene,Bezuidenhoudt, Barend C. B.. "Olefin Metathesis, p-Cresol, and the Second Generation Grubbs Catalyst: Fitting the Pieces". supporting information. p. 1752 - 1762. Retrieved 2021/05/06.