2-amino-6-(4-methoxyphenylthio)-9-{2-[bis(propionyloxymethoxy)phosphonomethoxy]-ethyl}-purine

Base Information

Chemical Name:2-amino-6-(4-methoxyphenylthio)-9-{2-[bis(propionyloxymethoxy)phosphonomethoxy]-ethyl}-purine
CAS No.:1309973-06-5
Molecular Formula:C₂₃H₃₀N₅O₉PS
Molecular Weight:583.559
Hs Code.:

Synonyms:2-amino-6-(4-methoxyphenylthio)-9-{2-[bis(propionyloxymethoxy)phosphonomethoxy]-ethyl}-purine

Suppliers and Price of 2-amino-6-(4-methoxyphenylthio)-9-{2-[bis(propionyloxymethoxy)phosphonomethoxy]-ethyl}-purine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 2-amino-6-(4-methoxyphenylthio)-9-{2-[bis(propionyloxymethoxy)phosphonomethoxy]-ethyl}-purine

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 2-amino-6-(4-methoxyphenylthio)-9-{2-[bis(propionyloxymethoxy)phosphonomethoxy]-ethyl}-purine

There total 3 articles about 2-amino-6-(4-methoxyphenylthio)-9-{2-[bis(propionyloxymethoxy)phosphonomethoxy]-ethyl}-purine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5402-53-9
chloromethyl propionate

: GCD-189

: 1309973-06-5
2-amino-6-(4-methoxyphenylthio)-9-{2-[bis(propionyloxymethoxy)phosphonomethoxy]-ethyl}-purine

Guidance literature:: GCD-189; With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 0.166667h; Inert atmosphere;

chloromethyl propionate; In N,N-dimethyl-formamide; at 20 ℃; for 35h; Inert atmosphere;

Reference yield:

: 183194-25-4
[[2-(2-amino-6-chloro-9H-purin-9-yl)ethoxy]methyl]phosphonic acid bis(1-methylethyl)ester

: 1309973-06-5
2-amino-6-(4-methoxyphenylthio)-9-{2-[bis(propionyloxymethoxy)phosphonomethoxy]-ethyl}-purine

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine / N,N-dimethyl-formamide / 4 h / 20 - 70 °C / Inert atmosphere

2.1: trimethylsilyl bromide / acetonitrile / 20 °C

3.1: triethylamine / N,N-dimethyl-formamide / 0.17 h / 20 °C / Inert atmosphere

3.2: 35 h / 20 °C / Inert atmosphere

With trimethylsilyl bromide; triethylamine; In N,N-dimethyl-formamide; acetonitrile;

Reference yield:

: 1309973-34-9
2-amino-6-(4-methoxyphenylthio)-9-{2-[bis(isopropyloxy)phosphonomethoxy]-ethyl}-purine

: 1309973-06-5
2-amino-6-(4-methoxyphenylthio)-9-{2-[bis(propionyloxymethoxy)phosphonomethoxy]-ethyl}-purine

Guidance literature:: Multi-step reaction with 2 steps

1.1: trimethylsilyl bromide / acetonitrile / 20 °C

2.1: triethylamine / N,N-dimethyl-formamide / 0.17 h / 20 °C / Inert atmosphere

2.2: 35 h / 20 °C / Inert atmosphere

With trimethylsilyl bromide; triethylamine; In N,N-dimethyl-formamide; acetonitrile;