Z-Gly-Gly-L-Phe-OCH₂CF₃

Base Information

• Chemical Name: Z-Gly-Gly-L-Phe-OCH₂CF₃
• CAS No.: 169676-30-6
• Molecular Formula: C₂₃H₂₄F₃N₃O₆
• Molecular Weight: 495.455

Synonyms:Z-Gly-Gly-L-Phe-OCH₂CF₃

Chemical Property of Z-Gly-Gly-L-Phe-OCH₂CF₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Z-Gly-Gly-L-Phe-OCH₂CF₃

There total 1 articles about Z-Gly-Gly-L-Phe-OCH₂CF₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

CbzGlyGly (2566-19-0) → Z-Gly-Gly-L-Phe-OCH2CF3 (169676-30-6)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1039/b108738j

Reference yield: 4.0%

(2S)-amino-4-methylpentanamide hydrochloride (10466-61-2) + Z-Gly-Gly-L-Phe-OCH2CF3 (169676-30-6) → CbzGlyGly (2566-19-0) + Z-Gly-Gly-L-Phe-L-Leu-NH2 (84969-56-2)

Guidance literature:

With Tris buffer; TEA; Celite; α-chymotrypsin; In acetonitrile; at 30 ℃; for 0.25h;

DOI:10.1039/P19960002867

Reference yield:

Z-Gly-Gly-L-Phe-OCH2CF3 (169676-30-6) → amide of N-t-butyloxycarbonyl-O-benzyl-L-tyrosylglycylglycyl-L-phenylalanyl-L-leucine (81638-88-2)

Guidance literature:

Multi-step reaction with 5 steps

1: 2.4 percent Chromat. / Et3N; α-chymotrypsin immobilised on Celite / acetonitrile; various solvent(s) / 0.08 h / 30 °C / pH 7.8

2: 100 percent / diethyl ether

3: 14.9 percent Chromat. / Et3N; α-chymotrypsin immobilised on Celite / acetonitrile; various solvent(s) / 0.08 h / 30 °C / pH 7.8

4: H₂ / 5percent Pd/C / methanol

5: 89 percent / Et₃N; EDC; HOBT / dimethylformamide / 20 °C

With α-chymotrypsin immobilised on Celite; hydrogen; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine; 5percent Pd/C; In methanol; diethyl ether; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1039/b108738j

upstream raw materials:

CbzGlyGly

Downstream raw materials:

CbzGlyGly

Z-Gly-Gly-L-Phe-L-Leu-NH₂

N-benzyloxycarbonyl-L-glycyl-L-glycyl-L-phenylalanine

Z-Gly-Gly-L-Phe-OMe

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 169676-30-6 Z-Gly-Gly-L-Phe-OCH₂CF₃

Send

Send

Metric Ton KG G Pound L ML

Send

Send