84969-56-2

Basic information

• Product Name: Z-Gly-Gly-L-Phe-L-Leu-NH₂
• Synonyms: Z-Gly-Gly-L-Phe-L-Leu-NH₂
• CAS NO: 84969-56-2
• Molecular Weight: 525.605
• Mol File: 84969-56-2.mol

Chemical Properties

• CAS DataBase Reference: Z-Gly-Gly-L-Phe-L-Leu-NH₂(CAS DataBase Reference)
• NIST Chemistry Reference: Z-Gly-Gly-L-Phe-L-Leu-NH₂(84969-56-2)
• EPA Substance Registry System: Z-Gly-Gly-L-Phe-L-Leu-NH₂(84969-56-2)

Safety Data

• Hazardous Substances Data: 84969-56-2(Hazardous Substances Data)

Upstream product

• 13171-93-2 N-benzyloxycarbonyl-L-glycyl-L-glycyl-L-phenylalanine 
• 38678-59-0 L-Phe-L-Leu-NH₂ 
• 35909-92-3 N-carbobenzoxy-L-phenylalanine methyl ester 
• 69193-15-3 N-(benzyloxycarbonyl)-glycyl-L-phenylalanyl-L-leucine amide 
• 69193-13-1 Cbz-L-Phe-L-Leu-NH₂ 
• 687-51-4 H-L-Leu-NH₂ 
• 252846-38-1 Z-Gly-Gly-L-Phe-OCam 
• 169676-30-6 Z-Gly-Gly-L-Phe-OCH₂CF₃ 
• 2566-19-0 CbzGlyGly 
• 10466-61-2 (2S)-amino-4-methylpentanamide hydrochloride 
• 15027-03-9 Z-Gly-Gly-L-Phe-OMe 
• 1145-81-9 ethyl 2-(benzyloxycarbonylamino)ethanoate 
• 71591-20-3 H-Gly-Phe-Leu-NH₂ 
• 84969-55-1 Phe-Leu-NH₂*HCOOH 

Downstream Products

• 71591-21-4 Z-Tyr-Gly-Gly-Phe-Leu-NH₂ 
• 79396-86-4 Boc-L-Tyr-Gly-Gly-L-Phe-L-Leu-NH₂ 
• 81638-88-2 amide of N-t-butyloxycarbonyl-O-benzyl-L-tyrosylglycylglycyl-L-phenylalanyl-L-leucine 
• 82948-92-3 [des-tyr¹]-leucine enkephalinamide 
• 100929-57-5 Glycylglycylphenylalanylleucinamide acetate 
• 84969-57-3 Gly-Gly-Phe-Leu-NH₂*HCOOH 

Relevant articles and documents

α-chymotrypsin-catalysed segment condensations via the kinetically controlled approach using carbamoylmethyl esters as acyl donors in organic media

The superiority of the carbamoylmethyl ester as an acyl donor for the α-chymotrypsin-catalysed segment condensations via the kinetically controlled approach is demonstrated in several model systems carried out in organic media with low water content. Furthermore, this approach is successfully applied to the construction of the Leu-enkephalin sequence via a 4 + 1 segment coupling.

Superiority of the carbamoylmethyl ester as an acyl donor for the protease-catalyzed kinetically controlled peptide synthesis in organic media: Application to segment condensations

The superiority of the carbamoylmethyl ester as an acyl donor for the α-chymotrypsin-catalyzed kinetically controlled peptide synthesis was demonstrated in several segment condensations carried out in organic media with low water content. Then this approach was successfully applied to the construction of the Leuenkephalin sequence via the 4 + 1 segment condensation.

α-Chymotrypsin-catalysed peptide synthesis using activated esters as acyl donors

The coupling efficiency in α-chymotrypsin-catalysed peptide synthesis is greatly improved by the use of activated esters such as the 2,2,2-trifluoroethyl ester as acyl donor instead of the conventional methyl ester; this approach is useful for the incorporation of non-protein amino acids into peptides.

Peptide Synthesis Mediated by Immobilized and Viable Baker's Yeast in Reverse Micelles: Synthesis of Leucine Enkephalin Analogues

Cells of baker's yeast (Saccharomyces cerevisiae NCIM 3305) immobilized in calcium alginate beads are found to be viable in reverse micelles of bis(2-ethylhexyl)sulphosuccinate sodium salt 1 in iso-octane for days and were used for the first time for pept

Papain Catalysed Peptide Synthesis: Control of Amidase Activity and the Introduction of Unusual Amino Acids

Procedures for the papain catalysed synthesis of peptides containing D-amino acids and derivatives with control of the enzyme's amidase activity have been developed.

Catalytic Transfer Hydrogenation in Pepetide Synthesis: Synthesis of 5- and 5-enkephalins

The simplicity in the removal of N-protecting groups like benzyloxycarbonyl employed in peptide synthesis by catalytic transfer hydrogenation at room temperature using formic acid in presence of palladium black has been demonstrated by the synthesis of the opioid pentapeptides 5- and 5-enkephalins.