N'-(4-cyano-2,3-difluoro-phenyl)-hydrazinecarboxylic acid tert-butyl ester

Base Information

• Chemical Name: N'-(4-cyano-2,3-difluoro-phenyl)-hydrazinecarboxylic acid tert-butyl ester
• CAS No.: 1073973-12-2
• Molecular Formula: C₁₂H₁₃F₂N₃O₂
• Molecular Weight: 269.251
• Mol file: 1073973-12-2.mol

Synonyms:N'-(4-cyano-2,3-difluoro-phenyl)-hydrazinecarboxylic acid tert-butyl ester

Chemical Property of N'-(4-cyano-2,3-difluoro-phenyl)-hydrazinecarboxylic acid tert-butyl ester

Chemical Property:

Purity/Quality:

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Technology Process of N'-(4-cyano-2,3-difluoro-phenyl)-hydrazinecarboxylic acid tert-butyl ester

There total 1 articles about N'-(4-cyano-2,3-difluoro-phenyl)-hydrazinecarboxylic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

t-butoxycarbonylhydrazine (870-46-2) + 2,3,4-trifluorobenzonitrile (143879-80-5) → N'-(4-cyano-2,3-difluoro-phenyl)-hydrazinecarboxylic acid tert-butyl ester (1073973-12-2)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; at 100 ℃; for 3h;

Reference yield: 72.0%

N'-(4-cyano-2,3-difluoro-phenyl)-hydrazinecarboxylic acid tert-butyl ester (1073973-12-2) + trifluoroacetic acid (76-05-1) → 2,3-difluoro-4-hydrazino-benzonitrile, trifluoroacetate (1073973-11-1)

Guidance literature:

In 1,2-dichloro-ethane; at 20 ℃; for 72h;

upstream raw materials:

t-butoxycarbonylhydrazine

2,3,4-trifluorobenzonitrile

Downstream raw materials:

2,3-difluoro-4-hydrazino-benzonitrile, trifluoroacetate