bis-N,N-(p-nitrophenyl-2,2-diphenylethyl-12-aminododecyl phosphate)fumaramide

Base Information

• Chemical Name: bis-N,N-(p-nitrophenyl-2,2-diphenylethyl-12-aminododecyl phosphate)fumaramide
• CAS No.: 906072-80-8
• Molecular Formula: C₆₈H₈₆N₄O₁₄P₂
• Molecular Weight: 1245.4
• Mol file: 906072-80-8.mol

Synonyms:bis-N,N-(p-nitrophenyl-2,2-diphenylethyl-12-aminododecyl phosphate)fumaramide

Chemical Property of bis-N,N-(p-nitrophenyl-2,2-diphenylethyl-12-aminododecyl phosphate)fumaramide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of bis-N,N-(p-nitrophenyl-2,2-diphenylethyl-12-aminododecyl phosphate)fumaramide

There total 8 articles about bis-N,N-(p-nitrophenyl-2,2-diphenylethyl-12-aminododecyl phosphate)fumaramide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phosphoric acid 2,2-diphenyl-ethyl ester bis-(4-nitro-phenyl) ester (906072-79-5) → bis-N,N-(p-nitrophenyl-2,2-diphenylethyl-12-aminododecyl phosphate)fumaramide (906072-80-8)

Guidance literature:

Multi-step reaction with 3 steps

1: DBU / toluene

2: trifluoroacetic acid / CH₂Cl₂ / 0.33 h

3: triethylamine / CHCl₃ / 3 h

With 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; trifluoroacetic acid; In dichloromethane; chloroform; toluene;

DOI:10.1021/ja0619253

Reference yield:

12-(tert-butylcarbamoyl)dodecyl-4-nitrophenyl-2,2-diphenylethyl phosphate (906072-85-3) → bis-N,N-(p-nitrophenyl-2,2-diphenylethyl-12-aminododecyl phosphate)fumaramide (906072-80-8)

Guidance literature:

Multi-step reaction with 2 steps

1: trifluoroacetic acid / CH₂Cl₂ / 0.33 h

2: triethylamine / CHCl₃ / 3 h

With triethylamine; trifluoroacetic acid; In dichloromethane; chloroform;

DOI:10.1021/ja0619253

Reference yield:

tris(p-nitrophenyl)phosphate (3871-20-3) → bis-N,N-(p-nitrophenyl-2,2-diphenylethyl-12-aminododecyl phosphate)fumaramide (906072-80-8)

Guidance literature:

Multi-step reaction with 4 steps

1: 90 percent / DBU / CHCl₃ / 3 h

2: DBU / toluene

3: trifluoroacetic acid / CH₂Cl₂ / 0.33 h

4: triethylamine / CHCl₃ / 3 h

With 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; trifluoroacetic acid; In dichloromethane; chloroform; toluene;

DOI:10.1021/ja0619253

upstream raw materials:

fumaryl dichloride

phosphoric acid 2,2-diphenyl-ethyl ester bis-(4-nitro-phenyl) ester

12-(tert-butylcarbamoyl)dodecyl-4-nitrophenyl-2,2-diphenylethyl phosphate

tris(p-nitrophenyl)phosphate