Difluoromethyl 3-methylphenyl sulphone

Base Information

Chemical Name:Difluoromethyl 3-methylphenyl sulphone
CAS No.:4837-16-5
Molecular Formula:C₈H₈F₂O₂S
Molecular Weight:206.213
Hs Code.:
DSSTox Substance ID:DTXSID001259595

Synonyms:Difluoromethyl 3-methylphenyl sulphone;4837-16-5;Benzene, 1-[(difluoromethyl)sulfonyl]-3-methyl-;SCHEMBL9733973;FHCGDMHFSHKZHY-UHFFFAOYSA-N;DTXSID001259595;1-(difluoromethylsulfonyl)-3-methylbenzene;1-[(Difluoromethyl)sulfonyl]-3-methylbenzene

Suppliers and Price of Difluoromethyl 3-methylphenyl sulphone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Difluoromethyl 3-methylphenyl sulphone

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:206.02130699
Heavy Atom Count:13
Complexity:256

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=CC=C1)S(=O)(=O)C(F)F

Technology Process of Difluoromethyl 3-methylphenyl sulphone

There total 3 articles about Difluoromethyl 3-methylphenyl sulphone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 75-45-6
Chlorodifluoromethane

: 15898-38-1
sodium 3-methylbenzenesulfinate

: 4837-16-5
Difluormethyl-m-tolyl-sulfon

Guidance literature:: With triethylamine; sodium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 5h; Sealed tube;

Reference yield: 65.0%

: C₁₄H₁₄N₂O₂S

: 2,2‐difluoro‐2‐(triphenylphosphonio)acetate

: 4837-16-5
Difluormethyl-m-tolyl-sulfon

Guidance literature:: With cesium bicarbonate; In cyclohexane; at 100 ℃; for 6h;
DOI:10.1039/c6ra20629h

Reference yield:

: 108-40-7
toluene-3-thiol

: 4837-16-5
Difluormethyl-m-tolyl-sulfon

Guidance literature:: Multi-step reaction with 2 steps

1: NaOH / dioxane; H₂O

2: aq. H₂O₂ / acetic acid

With sodium hydroxide; dihydrogen peroxide; In 1,4-dioxane; water; acetic acid;