C₂₆H₂₄N₄O₂

Base Information

• Chemical Name: C₂₆H₂₄N₄O₂
• CAS No.: 1609254-98-9
• Molecular Formula: C₂₆H₂₄N₄O₂
• Molecular Weight: 424.502
• Mol file: 1609254-98-9.mol

Synonyms:C₂₆H₂₄N₄O₂

Chemical Property of C₂₆H₂₄N₄O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₆H₂₄N₄O₂

There total 5 articles about C₂₆H₂₄N₄O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

2,4-diacetyl-5-hydroxy-3-(3-(2-hydroxyphenyl)-1-phenyl-1H-pyrazol-4-yl)-5-methylcyclohexanone (1609254-94-5) → C26H24N4O2 (1609254-98-9)

Guidance literature:

With hydrazine hydrate; In methanol; for 7h; Reflux;

DOI:10.1080/00397911.2013.862724

Reference yield:

phenylhydrazine (100-63-0) → C26H24N4O2 (1609254-98-9)

Guidance literature:

Multi-step reaction with 4 steps

1: acetic acid / methanol / 1 h / Reflux

2: potassium carbonate; trichlorophosphate / 6 h / 0 - 80 °C

3: piperidine / dimethyl sulfoxide / 10 h / Reflux

4: hydrazine hydrate / methanol / 7 h / Reflux

With piperidine; potassium carbonate; hydrazine hydrate; acetic acid; trichlorophosphate; In methanol; dimethyl sulfoxide;

DOI:10.1080/00397911.2013.862724

Reference yield:

o-hydroxyacetophenone (118-93-4,104809-67-8) → C26H24N4O2 (1609254-98-9)

Guidance literature:

Multi-step reaction with 4 steps

1: acetic acid / methanol / 1 h / Reflux

2: potassium carbonate; trichlorophosphate / 6 h / 0 - 80 °C

3: piperidine / dimethyl sulfoxide / 10 h / Reflux

4: hydrazine hydrate / methanol / 7 h / Reflux

With piperidine; potassium carbonate; hydrazine hydrate; acetic acid; trichlorophosphate; In methanol; dimethyl sulfoxide;

DOI:10.1080/00397911.2013.862724

upstream raw materials:

phenylhydrazine

o-hydroxyacetophenone

2-[1-(2-phenylhydrazino)ethyl]phenol

2,4-diacetyl-5-hydroxy-3-(3-(2-hydroxyphenyl)-1-phenyl-1H-pyrazol-4-yl)-5-methylcyclohexanone

Refernces