2-acetylamino 3-nitro phenol

Base Information

• Chemical Name: 2-acetylamino 3-nitro phenol
• CAS No.: 59820-29-0
• Molecular Formula: C₈H₈N₂O₄
• Molecular Weight: 196.163
• Mol file: 59820-29-0.mol

Synonyms:2-acetylamino 3-nitro phenol

Chemical Property of 2-acetylamino 3-nitro phenol

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-acetylamino 3-nitro phenol

There total 6 articles about 2-acetylamino 3-nitro phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-acetoxy 6-nitro acetanilide + acetoxy-acetic acid anilide (56609-07-5) + Ac-Gca-pNA (171416-09-4) → 2-acetylamino 3-nitro phenol (59820-29-0)

Guidance literature:

With sodium hydroxide; nitric acid; In acetic anhydride;

Reference yield:

1-acetoxy-2-acetylamino-3-nitro-benzene (69194-51-0) → 2-acetylamino 3-nitro phenol (59820-29-0)

Guidance literature:

With sodium hydroxide;

Reference yield:

2-Amino-3-nitrophenol (603-85-0) → 2-acetylamino 3-nitro phenol (59820-29-0)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / CH₂Cl₂ / 18 h / 0 - 20 °C

2: K₂CO₃ / methanol / 2 h / 20 °C

With potassium carbonate; triethylamine; In methanol; dichloromethane;

DOI:10.1016/j.bmcl.2006.08.010

upstream raw materials:

1-acetoxy-2-acetylamino-3-nitro-benzene

2-Amino-3-nitrophenol

acetic anhydride

2-acetamidophenyl acetate

Downstream raw materials:

ethyl 4-[2-(acetylamino)-3-nitrophenoxy]butanoate

2-acetyl-3-nitrophenyl (2-ethoxyethyl) ether

2-nitro-6-pentyloxy-phenylamine

N-(2-Nitro-6-pentyloxy-phenyl)-acetamide