(2R,3R,4S,5S)-5-(tert-butyldiphenylsilanyloxymethyl)-1,2:4,5-di-O-isopropylidenedioxy-3-methoxy-6-heptene

Base Information

Chemical Name:(2R,3R,4S,5S)-5-(tert-butyldiphenylsilanyloxymethyl)-1,2:4,5-di-O-isopropylidenedioxy-3-methoxy-6-heptene
CAS No.:870862-49-0
Molecular Formula:C₃₁H₄₄O₆Si
Molecular Weight:540.772
Hs Code.:

Synonyms:(2R,3R,4S,5S)-5-(tert-butyldiphenylsilanyloxymethyl)-1,2:4,5-di-O-isopropylidenedioxy-3-methoxy-6-heptene

Suppliers and Price of (2R,3R,4S,5S)-5-(tert-butyldiphenylsilanyloxymethyl)-1,2:4,5-di-O-isopropylidenedioxy-3-methoxy-6-heptene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,3R,4S,5S)-5-(tert-butyldiphenylsilanyloxymethyl)-1,2:4,5-di-O-isopropylidenedioxy-3-methoxy-6-heptene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,3R,4S,5S)-5-(tert-butyldiphenylsilanyloxymethyl)-1,2:4,5-di-O-isopropylidenedioxy-3-methoxy-6-heptene

There total 4 articles about (2R,3R,4S,5S)-5-(tert-butyldiphenylsilanyloxymethyl)-1,2:4,5-di-O-isopropylidenedioxy-3-methoxy-6-heptene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 870862-48-9
(2R,3R,4S,5S)-5-(tert-butyldiphenylsilanyloxymethyl)-1,2:4,5-di-O-isopropylidenedioxy-6-hepten-3-ol

: 74-88-4
methyl iodide

: 870862-49-0
(2R,3R,4S,5S)-5-(tert-butyldiphenylsilanyloxymethyl)-1,2:4,5-di-O-isopropylidenedioxy-3-methoxy-6-heptene

Guidance literature:: With sodium hydride; In tetrahydrofuran; at 0 ℃; for 4h;
DOI:10.1021/jo051686m

Reference yield:

: 870862-47-8
(2S,3S,4R,5R)-2-C-(tert-butyldiphenylsilanyloxymethyl)-2,3:5,6-di-O-isopropylidene-D-mannofuranose

: 870862-49-0
(2R,3R,4S,5S)-5-(tert-butyldiphenylsilanyloxymethyl)-1,2:4,5-di-O-isopropylidenedioxy-3-methoxy-6-heptene

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium tert-butoxide / toluene / 1 h / 105 °C

1.2: 97 percent / toluene / 2 h / 105 °C

2.1: 97 percent / NaH / various solvent(s); tetrahydrofuran / 4 h / 0 °C

With potassium tert-butylate; sodium hydride; In tetrahydrofuran; toluene; 1.2: Wittig reaction;
DOI:10.1021/jo051686m

Reference yield:

: 1779-49-3
Methyltriphenylphosphonium bromide

: 870862-49-0
(2R,3R,4S,5S)-5-(tert-butyldiphenylsilanyloxymethyl)-1,2:4,5-di-O-isopropylidenedioxy-3-methoxy-6-heptene

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium tert-butoxide / toluene / 1 h / 105 °C

1.2: 97 percent / toluene / 2 h / 105 °C

2.1: 97 percent / NaH / various solvent(s); tetrahydrofuran / 4 h / 0 °C

With potassium tert-butylate; sodium hydride; In tetrahydrofuran; toluene; 1.2: Wittig reaction;
DOI:10.1021/jo051686m