(2Z)-N-(4-[(2-tert-butylaminosulfonyl)phenyl]phenyl)-3-(3-cyanophenyl)-acrylamide

Base Information

Chemical Name:(2Z)-N-(4-[(2-tert-butylaminosulfonyl)phenyl]phenyl)-3-(3-cyanophenyl)-acrylamide
CAS No.:288309-01-3
Molecular Formula:C₂₆H₂₅N₃O₃S
Molecular Weight:459.569
Hs Code.:

Synonyms:(2Z)-N-(4-[(2-tert-butylaminosulfonyl)phenyl]phenyl)-3-(3-cyanophenyl)-acrylamide

Suppliers and Price of (2Z)-N-(4-[(2-tert-butylaminosulfonyl)phenyl]phenyl)-3-(3-cyanophenyl)-acrylamide

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Chemical Property of (2Z)-N-(4-[(2-tert-butylaminosulfonyl)phenyl]phenyl)-3-(3-cyanophenyl)-acrylamide

Chemical Property:

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Technology Process of (2Z)-N-(4-[(2-tert-butylaminosulfonyl)phenyl]phenyl)-3-(3-cyanophenyl)-acrylamide

There total 2 articles about (2Z)-N-(4-[(2-tert-butylaminosulfonyl)phenyl]phenyl)-3-(3-cyanophenyl)-acrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 75-24-1
trimethylaluminum

: 193151-10-9
3-(3-cyano-phenyl)-acrylic acid methyl ester

: 193006-34-7
4-(2'-tert-butylaminosulfonylphenyl)aniline

: 288309-01-3
(2Z)-N-(4-[(2-tert-butylaminosulfonyl)phenyl]phenyl)-3-(3-cyanophenyl)-acrylamide

Guidance literature:: In hexane; dichloromethane; water;

Reference yield:

: 203512-53-2
methyl cis-3-cyanocinnamate

: 193006-34-7
4-(2'-tert-butylaminosulfonylphenyl)aniline

: 288309-01-3
(2Z)-N-(4-[(2-tert-butylaminosulfonyl)phenyl]phenyl)-3-(3-cyanophenyl)-acrylamide

Guidance literature:: With trimethylaluminum; In dichloromethane;
DOI:10.1016/S0960-894X(02)00199-3

Reference yield:

: 288309-01-3
(2Z)-N-(4-[(2-tert-butylaminosulfonyl)phenyl]phenyl)-3-(3-cyanophenyl)-acrylamide

: (2Z)-N-(4-[(2-aminosulfonyl)phenyl]phenyl)-3-(3-amidinophenyl)-acrylamide

Guidance literature:: Multi-step reaction with 2 steps

1: HCl(g); MeOH

2: NH₄OAc

With hydrogenchloride; methanol; ammonium acetate; 1: Pinner reaction;
DOI:10.1016/S0960-894X(02)00199-3