193151-10-9

Basic information

• Product Name: 3-(3-CYANO-PHENYL)-ACRYLIC ACID METHYL ESTER
• Synonyms: METHYL 3-(3-CYANOPHENYL)ACRYLATE;3-(3-CYANO-PHENYL)-ACRYLIC ACID METHYL ESTER
• CAS NO: 193151-10-9
• Molecular Formula: C₁₁H₉NO₂
• Molecular Weight: 187.19
• Mol File: 193151-10-9.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 321.3±25.0 °C(Predicted)
• Appearance: /
• Density: 1.15±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 3-(3-CYANO-PHENYL)-ACRYLIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-CYANO-PHENYL)-ACRYLIC ACID METHYL ESTER(193151-10-9)
• EPA Substance Registry System: 3-(3-CYANO-PHENYL)-ACRYLIC ACID METHYL ESTER(193151-10-9)

Safety Data

• Hazardous Substances Data: 193151-10-9(Hazardous Substances Data)

Upstream product

• 24964-64-5 3-Cyanobenzaldehyde 
• 1779-58-4 (methyloxycarbonylmethyl)triphenylphosphonium bromide 
• 67-56-1 methanol 
• 16642-93-6 (3E)-3-(3-cyanophenyl)acrylic acid 
• 79432-87-4 methyl m-bromocinnamate 
• 5927-18-4 trimethyl phosphonoacetate 
• 69113-59-3 3-iodobenzonitrile 
• 292638-85-8 acrylic acid methyl ester 
• 71093-81-7 (E)-methyl 3-(3-formylphenyl)acrylate 
• 21204-67-1 methyl (triphenylphosphoranylidene)acetate 
• 88738-78-7 bis-(2,2,2-trifluoroethyl)(methoxycarbonylmethyl)phosphonate 
• 6952-59-6 3-cyanobromobenzene 

Downstream Products

• 16642-93-6 (3E)-3-(3-cyanophenyl)acrylic acid 
• 223489-88-1 3-(3-{[Benzenesulfonyl-(4-pyrazol-1-yl-benzyl)-amino]-methyl}-phenyl)-2-methyl-propionic acid 
• 223491-42-7 3-(3-aminomethyl-phenyl)-2-methyl-propionic acid methyl ester 
• 223491-46-1 3-(3-{[(1-Methyl-1 H-imidazole-4-sulfonyl)-(4-pyrazin-2-yl-benzyl)-amino]-methyl}-phenyl)-propionic acid methyl ester 
• 223491-73-4 3-{3-[(4-isobutyl-benzylamino)-methyl]-phenyl}-propionic acid methyl ester 
• 223489-78-9 3-(3-{[(4-Chloro-benzenesulfonyl)-(4-pyrazin-2-yl-benzyl)-amino]-methyl}-phenyl)-propionic acid 
• 223490-07-1 3-(3{[(2,3-Dihydro-benzofuran-5-ylmethyl)-(4-fluoro-benzenesulfonyl)-amino]-methyl}-phenyl)-propionic acid 
• 223491-26-7 3-(3-{[(4-chloro-benzenesulfonyl)-(4-pyrazin-2-yl-benzyl)-amino]-methyl}-phenyl)-propionic acid methyl ester 
• 223491-54-1 3-(3-{[(4-chloro-benzenesulfonyl)-(4-thiazol-2-yl-benzyl)-amino]-methyl}-phenyl)-propionic acid methyl ester 
• 223489-79-0 3-(3-{[Benzenesulfonyl-(4-thiazol-2-yl-benzyl)-amino]-methyl}-phenyl)-propionic acid 
• 223491-28-9 3-(3-{[benzenesulfonyl-(4-thiazol-2-yl-benzyl)-amino]-methyl}-phenyl)-propionic acid methyl ester 
• 223490-93-5 3-(3-{[(1-methyl-1H-imidazole-4-sulfonyl)-(4-thiazol-2-yl-benzyl)-amino]-methyl}-phenyl)-propionic acid methyl ester 
• 223489-67-6 3-(3-{[(Pyridine-2-sulfonyl)-(4-thiazol-2-yl-benzyl)-amino]-methyl}-phenyl)-propionic acid 
• 223491-14-3 3-(3-{[(Pyridine-2-sulfonyl)-(4-thiazol-2-yl-benzyl)-amino]-methyl}-phenyl)-propionic acid methyl ester 

Relevant articles and documents

Phosphine-Functionalized Chitosan Microparticles as Support Materials for Palladium Nanoparticles in Heck Reactions

Herein, we investigated the activation and stabilization of Pd nanoparticles using microparticles of chitosan-functionalized with phosphine moieties. The catalytic activity of the prepared material was assessed in a series of Heck reactions, which demonst

Cascade Process for Direct Transformation of Aldehydes (RCHO) to Nitriles (RCN) Using Inorganic Reagents NH2OH/Na2CO3/SO2F2 in DMSO

A simple, mild, and practical process for direct conversion of aldehydes to nitriles was developed feathering a wide substrate scope and great functional group tolerability (52 examples, over 90% yield in most cases) using inorganic reagents (NH2OH/Na2CO3/SO2F2) in DMSO. This method allows for transformations of readily available, inexpensive, and abundant aldehydes to highly valuable nitriles in a pot, atom, and step-economical manner without transition metals. This protocol will serve as a robust tool for the installation of cyano-moieties to complicated molecules.

A robust first-pass protocol for the heck-mizoroki reaction

The Heck-Mizoroki (HM) reaction is one of the most widely used C-C bond-forming methods of contemporary synthesis. Notwithstanding this, these reactions frequently require significant optimization before efficient transformations can be obtained. We describe here the results of a study that aimed to establish a generic experimental protocol for HM reactions which enables acceptable yields from first-pass experiments. The methodology utilizes readily available stable catalysts and can be applied to a broad range of coupling partners.