Cyclopropanecarboxaldehyde, 2-[(acetyloxy)methyl]-, (1R,2S)- (9CI)

Base Information

Chemical Name:Cyclopropanecarboxaldehyde, 2-[(acetyloxy)methyl]-, (1R,2S)- (9CI)
CAS No.:166762-22-7
Molecular Formula:C₇H₁₀O₃
Molecular Weight:142.155
Hs Code.:
Mol file:166762-22-7.mol

Synonyms:Cyclopropanecarboxaldehyde,2-[(acetyloxy)methyl]-, (1R-cis)-

Suppliers and Price of Cyclopropanecarboxaldehyde, 2-[(acetyloxy)methyl]-, (1R,2S)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 2 raw suppliers

Chemical Property of Cyclopropanecarboxaldehyde, 2-[(acetyloxy)methyl]-, (1R,2S)- (9CI)

Chemical Property:

PSA：43.37000
LogP:0.38450

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of Cyclopropanecarboxaldehyde, 2-[(acetyloxy)methyl]-, (1R,2S)- (9CI)

There total 3 articles about Cyclopropanecarboxaldehyde, 2-[(acetyloxy)methyl]-, (1R,2S)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.1%

: 123809-77-8
(1S,2R)-2-(hydroxymethyl)cyclopropane-1-methyl acetate

: 166762-22-7,397274-64-5
(1R,2S)-2-acetoxymethyl-1-formylcyclopropane

Guidance literature:: With oxalyl dichloride; dimethyl sulfoxide; In dichloromethane; at -50 ℃; for 0.25h;
DOI:10.1002/hlca.19920750309

Reference yield:

: 98516-04-2,118014-41-8,123809-77-8
Acetic acid (1R,2S)-2-hydroxymethyl-cyclopropylmethyl ester

: 98516-04-2
(1R,2S)-1-acetoxymethyl-2-hydroxymethylcyclopropane

: 123809-77-8
(1S,2R)-2-(hydroxymethyl)cyclopropane-1-methyl acetate

: 166762-22-7,397274-64-5
(1R,2S)-2-acetoxymethyl-1-formylcyclopropane

: 397274-64-5
(1S,2R)-2-acetoxymethyl-1-formylcyclopropane

Guidance literature:: With tert.-butylhydroperoxide; sodium citrate buffer; chloroperoxidase; polyethylenimine; at 20 ℃; for 1h; pH=5.5; Title compound not separated from byproducts.;
DOI:10.1021/jo016161i

Reference yield:

: 2345-68-8,192056-11-4
((1R,2S)-2-Hydroxymethyl-cyclopropyl)-methanol

: 166762-22-7,397274-64-5
(1R,2S)-2-acetoxymethyl-1-formylcyclopropane

Guidance literature:: Multi-step reaction with 2 steps

1: 68.2 percent / 10 °C / porcine pancreas lipase

2: 90.1 percent / (COCl)2, DMSO / CH₂Cl₂ / 0.25 h / -50 °C

With oxalyl dichloride; dimethyl sulfoxide; In dichloromethane;
DOI:10.1002/hlca.19920750309