(E)-4-((E)-3-(4-chlorophenyl)-3-oxoprop-1-enyl)-6-((2-(7-chloroquinolin-4-ylamino)ethylamino)methylene)-2-methylcyclohexa-2,4-dienone

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Chemical Name:(E)-4-((E)-3-(4-chlorophenyl)-3-oxoprop-1-enyl)-6-((2-(7-chloroquinolin-4-ylamino)ethylamino)methylene)-2-methylcyclohexa-2,4-dienone
CAS No.:1375171-16-6
Molecular Formula:C₂₈H₂₃Cl₂N₃O₂
Molecular Weight:504.416
Hs Code.:

Synonyms:(E)-4-((E)-3-(4-chlorophenyl)-3-oxoprop-1-enyl)-6-((2-(7-chloroquinolin-4-ylamino)ethylamino)methylene)-2-methylcyclohexa-2,4-dienone

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Chemical Property of (E)-4-((E)-3-(4-chlorophenyl)-3-oxoprop-1-enyl)-6-((2-(7-chloroquinolin-4-ylamino)ethylamino)methylene)-2-methylcyclohexa-2,4-dienone

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Technology Process of (E)-4-((E)-3-(4-chlorophenyl)-3-oxoprop-1-enyl)-6-((2-(7-chloroquinolin-4-ylamino)ethylamino)methylene)-2-methylcyclohexa-2,4-dienone

There total 5 articles about (E)-4-((E)-3-(4-chlorophenyl)-3-oxoprop-1-enyl)-6-((2-(7-chloroquinolin-4-ylamino)ethylamino)methylene)-2-methylcyclohexa-2,4-dienone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 5407-57-8
N-(7-chloroquinolin-4-yl)ethylenediamine

: 1360827-45-7
C₁₇H₁₃ClO₃

: 1375171-16-6
(E)-4-((E)-3-(4-chlorophenyl)-3-oxoprop-1-enyl)-6-((2-(7-chloroquinolin-4-ylamino)ethylamino)methylene)-2-methylcyclohexa-2,4-dienone

Guidance literature:: In ethanol; at 20 ℃; for 0.166667h;
DOI:10.1016/j.bmc.2012.03.011

Reference yield:

: 99-91-2
para-chloroacetophenone

: 1375171-16-6
(E)-4-((E)-3-(4-chlorophenyl)-3-oxoprop-1-enyl)-6-((2-(7-chloroquinolin-4-ylamino)ethylamino)methylene)-2-methylcyclohexa-2,4-dienone

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / 1,4-dioxane; water / 80 - 90 °C

2: ethanol / 0.17 h / 20 °C

With hydrogenchloride; In 1,4-dioxane; ethanol; water;
DOI:10.1016/j.bmc.2012.03.011

Reference yield:

: 3328-73-2
4-hydroxy-5-methylisophthalaldehyde

: 1375171-16-6
(E)-4-((E)-3-(4-chlorophenyl)-3-oxoprop-1-enyl)-6-((2-(7-chloroquinolin-4-ylamino)ethylamino)methylene)-2-methylcyclohexa-2,4-dienone

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / 1,4-dioxane; water / 80 - 90 °C

2: ethanol / 0.17 h / 20 °C

With hydrogenchloride; In 1,4-dioxane; ethanol; water;
DOI:10.1016/j.bmc.2012.03.011