L-erythro-Pentonic acid, 2-deoxy-2,2-difluoro-4,5-O-(1-methylethylidene)-, ethyl ester

Base Information Edit

Chemical Name:L-erythro-Pentonic acid, 2-deoxy-2,2-difluoro-4,5-O-(1-methylethylidene)-, ethyl ester
CAS No.:166376-97-2
Molecular Formula:C₁₀H₁₆F₂O₅
Molecular Weight:254.231
Hs Code.:
DSSTox Substance ID:DTXSID30443481
Wikidata:Q82261339
Mol file:166376-97-2.mol

Synonyms:166376-97-2;ethyl (3S)-3-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-difluoro-3-hydroxypropanoate;L-erythro-Pentonic acid, 2-deoxy-2,2-difluoro-4,5-O-(1-methylethylidene)-, ethyl ester;2-DEOXY-2,2-DIFLUORO-4,5-O-(1-METHYLETHYLIDENE)-L-ERYTHRO-PENTONIC ACID, ETHYL ESTER;DTXSID30443481;OUFRYOWGFSOSEY-BQBZGAKWSA-N;AKOS015965809;AC-20157;L-Erythro-pentonic acid,2-deoxy-2,2-difluoro-4,5-O-(1-methylethylidene)-,ethyl ester

Suppliers and Price of L-erythro-Pentonic acid, 2-deoxy-2,2-difluoro-4,5-O-(1-methylethylidene)-, ethyl ester

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of L-erythro-Pentonic acid, 2-deoxy-2,2-difluoro-4,5-O-(1-methylethylidene)-, ethyl ester Edit

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.428
Boiling Point:338.388°C at 760 mmHg
Flash Point:158.451°C
PSA：64.99000
Density:1.232g/cm³
LogP:0.69720
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:254.09657993
Heavy Atom Count:17
Complexity:292

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(C(C1COC(O1)(C)C)O)(F)F
Isomeric SMILES:CCOC(=O)C([C@H]([C@@H]1COC(O1)(C)C)O)(F)F

Technology Process of L-erythro-Pentonic acid, 2-deoxy-2,2-difluoro-4,5-O-(1-methylethylidene)-, ethyl ester

There total 27 articles about L-erythro-Pentonic acid, 2-deoxy-2,2-difluoro-4,5-O-(1-methylethylidene)-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.6%

: 942296-13-1
ethyl (D-erythro)-3-(4-chlorophenylcarbamoyloxy)-2,2-difluoro-3-(2,2-dimethyl-dioxalane-4-yl)propionate

: 151900-33-3
1,1-diethyloxy-3-(4-chlorophenyl)urea

: 95058-92-7,166376-97-2
(erytro) ethyl-3-(2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-difluoro-3-hydroxy propionate

Guidance literature:: With morpholine; copper diacetate; In toluene; for 6h; Heating / reflux;

Reference yield: 92.0%

: 383-62-0
ethyl 2-chloro-2,2-difluoroacetate

: 15186-48-8
2,3-isopropylidene-glyceraldehyde

: 95058-92-7,166376-97-2
ethyl 2,2-difluoro-3(R)-hydroxy-3-(2,2-dimethyl-1,3-dioxolan-4-yl)propionate

Guidance literature:: ethyl 2-chloro-2,2-difluoroacetate; With chloro-trimethyl-silane; magnesium; In tetrahydrofuran; at 40 - 45 ℃; for 1h;

2,3-isopropylidene-glyceraldehyde; In tetrahydrofuran; at 40 - 45 ℃; for 1h;

With hydrogenchloride; In tetrahydrofuran; ethyl acetate; for 0.25h; Solvent; Temperature;