Technology Process of C24H35FN2O3
There total 10 articles about C24H35FN2O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(2S,5S)-tert-butyl 2-methyl-5-(2-oxoethyl)pyrrolidine-1-carboxylate; 4-(4-fluorobenzoyl)piperidine hydrochloride;
With
sodium tris(acetoxy)borohydride;
In
tetrahydrofuran;
at 20 ℃;
for 1h;
With
sodium hydrogencarbonate;
In
tetrahydrofuran; water; ethyl acetate;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: water; sodium hydroxide / methanol / 3 h / 100 °C
1.2: pH 4 - 5
2.1: borane-THF / tetrahydrofuran / 0.5 h / 20 °C
2.2: 2 h / 90 °C
3.1: sulfur trioxide pyridine complex; triethylamine / dimethyl sulfoxide / chloroform / 1 h / 20 °C
4.1: sodium tris(acetoxy)borohydride / tetrahydrofuran / 1 h / 20 °C
With
borane-THF; water; sulfur trioxide pyridine complex; sodium tris(acetoxy)borohydride; triethylamine; sodium hydroxide;
dimethyl sulfoxide;
In
tetrahydrofuran; methanol; chloroform;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: dimethyl sulfoxide / 3 h / 70 °C
2.1: water; sodium hydroxide / methanol / 3 h / 100 °C
2.2: pH 4 - 5
3.1: borane-THF / tetrahydrofuran / 0.5 h / 20 °C
3.2: 2 h / 90 °C
4.1: sulfur trioxide pyridine complex; triethylamine / dimethyl sulfoxide / chloroform / 1 h / 20 °C
5.1: sodium tris(acetoxy)borohydride / tetrahydrofuran / 1 h / 20 °C
With
borane-THF; water; sulfur trioxide pyridine complex; sodium tris(acetoxy)borohydride; triethylamine; sodium hydroxide;
dimethyl sulfoxide;
In
tetrahydrofuran; methanol; chloroform; dimethyl sulfoxide;
