.beta.-D-Allopyranose, 2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3-O-(phenylmethyl)-4,6-O-(phenylmethylene)-, 1-(2,2,2-trichloroethanimidate)

Base Information

Chemical Name:.beta.-D-Allopyranose, 2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3-O-(phenylmethyl)-4,6-O-(phenylmethylene)-, 1-(2,2,2-trichloroethanimidate)
CAS No.:165874-24-8
Molecular Formula:C₃₀H₂₅Cl₃N₂O₇
Molecular Weight:631.897
Hs Code.:

Synonyms:.beta.-D-Allopyranose, 2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3-O-(phenylmethyl)-4,6-O-(phenylmethylene)-, 1-(2,2,2-trichloroethanimidate)

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Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of .beta.-D-Allopyranose, 2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3-O-(phenylmethyl)-4,6-O-(phenylmethylene)-, 1-(2,2,2-trichloroethanimidate)

Chemical Property:

PSA：107.38000
LogP:5.47740

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of .beta.-D-Allopyranose, 2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3-O-(phenylmethyl)-4,6-O-(phenylmethylene)-, 1-(2,2,2-trichloroethanimidate)

There total 12 articles about .beta.-D-Allopyranose, 2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3-O-(phenylmethyl)-4,6-O-(phenylmethylene)-, 1-(2,2,2-trichloroethanimidate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 545-06-2
trichloroacetonitrile

: 165874-23-7
3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-phthalimido-β-D-allopyranose

: 165874-24-8
2,2,2-Trichloro-acetimidic acid (4aR,6S,7R,8S,8aS)-8-benzyloxy-7-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yl ester

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 0 ℃; for 0.25h;

Reference yield:

: 100-39-0
benzyl bromide

: 165874-24-8
2,2,2-Trichloro-acetimidic acid (4aR,6S,7R,8S,8aS)-8-benzyloxy-7-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 94 percent / barium oxide, barium hydroxide / dimethylformamide / 16 h / 20 °C

2: 1.) KOH / 1.) CH₃OH, H₂O, 125 deg C, 5 d, 2.) CHCl₃, 20 deg C, 20 min

3: 89 percent / 2)2>PF₆ / tetrahydrofuran / 1.5 h

4: 91 percent / HgCl₂ / acetone; H₂O / 3 h / 20 °C

5: 4A MS, DBU / CH₂Cl₂ / 0.25 h / 0 °C

With barium dihydroxide; potassium hydroxide; (1,5-cyclooctadiene)bis(methyldiphenylphosphine) iridium hexafluorophosphate; 1,8-diazabicyclo[5.4.0]undec-7-ene; mercury dichloride; barium(II) oxide; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; acetone;

Reference yield:

: 85-44-9
phthalic anhydride

: 165874-24-8
2,2,2-Trichloro-acetimidic acid (4aR,6S,7R,8S,8aS)-8-benzyloxy-7-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) KOH / 1.) CH₃OH, H₂O, 125 deg C, 5 d, 2.) CHCl₃, 20 deg C, 20 min

2: 89 percent / 2)2>PF₆ / tetrahydrofuran / 1.5 h

3: 91 percent / HgCl₂ / acetone; H₂O / 3 h / 20 °C

4: 4A MS, DBU / CH₂Cl₂ / 0.25 h / 0 °C

With potassium hydroxide; (1,5-cyclooctadiene)bis(methyldiphenylphosphine) iridium hexafluorophosphate; 1,8-diazabicyclo[5.4.0]undec-7-ene; mercury dichloride; In tetrahydrofuran; dichloromethane; water; acetone;