1-azido-1,2-dideoxy-3,4:5,6-di-O-isopropylidene-2-(N-p-nitrobenzenesulfonyl)amino-D-mannitol

Base Information

Chemical Name:1-azido-1,2-dideoxy-3,4:5,6-di-O-isopropylidene-2-(N-p-nitrobenzenesulfonyl)amino-D-mannitol
CAS No.:368878-38-0
Molecular Formula:C₁₈H₂₅N₅O₈S
Molecular Weight:471.491
Hs Code.:

Synonyms:1-azido-1,2-dideoxy-3,4:5,6-di-O-isopropylidene-2-(N-p-nitrobenzenesulfonyl)amino-D-mannitol

Suppliers and Price of 1-azido-1,2-dideoxy-3,4:5,6-di-O-isopropylidene-2-(N-p-nitrobenzenesulfonyl)amino-D-mannitol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-azido-1,2-dideoxy-3,4:5,6-di-O-isopropylidene-2-(N-p-nitrobenzenesulfonyl)amino-D-mannitol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-azido-1,2-dideoxy-3,4:5,6-di-O-isopropylidene-2-(N-p-nitrobenzenesulfonyl)amino-D-mannitol

There total 4 articles about 1-azido-1,2-dideoxy-3,4:5,6-di-O-isopropylidene-2-(N-p-nitrobenzenesulfonyl)amino-D-mannitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 368878-37-9
1,2-dideoxy-3,4:5,6-di-O-isopropylidene-1,2-(N-p-nitrobenzenesulfonyl)imino-D-mannitol

: 368878-38-0
1-azido-1,2-dideoxy-3,4:5,6-di-O-isopropylidene-2-(N-p-nitrobenzenesulfonyl)amino-D-mannitol

Guidance literature:: With sodium azide; In N,N-dimethyl-formamide; at 90 ℃; for 8h;
DOI:10.1016/S0040-4020(01)00650-0

Reference yield:

: 98-74-8
4-Nitrobenzenesulfonyl chloride

: 368878-38-0
1-azido-1,2-dideoxy-3,4:5,6-di-O-isopropylidene-2-(N-p-nitrobenzenesulfonyl)amino-D-mannitol

Guidance literature:: Multi-step reaction with 4 steps

1: Na₂CO₃ / CH₂Cl₂; H₂O / 1 h / 20 °C

2: 14.13 g / pyridine / CH₂Cl₂ / 1 h / 0 °C

3: 74 percent / NaH / tetrahydrofuran / 4 h / 20 °C

4: 98 percent / NaN₃ / dimethylformamide / 8 h / 90 °C

With pyridine; sodium azide; sodium hydride; sodium carbonate; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)00650-0

Reference yield:

: N-[(S)-2-Hydroxy-2-((4R,5R,4'R)-2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl]-5-yl)-ethyl]-4-nitro-benzenesulfonamide

: 368878-38-0
1-azido-1,2-dideoxy-3,4:5,6-di-O-isopropylidene-2-(N-p-nitrobenzenesulfonyl)amino-D-mannitol

Guidance literature:: Multi-step reaction with 3 steps

1: 14.13 g / pyridine / CH₂Cl₂ / 1 h / 0 °C

2: 74 percent / NaH / tetrahydrofuran / 4 h / 20 °C

3: 98 percent / NaN₃ / dimethylformamide / 8 h / 90 °C

With pyridine; sodium azide; sodium hydride; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)00650-0