2-(4-((4-(dimethylamino)phenyl)(hydroxy)(phenyl)methyl)phenoxy)ethan-1-ol

Base Information

• Chemical Name: 2-(4-((4-(dimethylamino)phenyl)(hydroxy)(phenyl)methyl)phenoxy)ethan-1-ol
• CAS No.: 1609033-85-3
• Molecular Formula: C₂₃H₂₅NO₃
• Molecular Weight: 363.456
• Mol file: 1609033-85-3.mol

Synonyms:2-(4-((4-(dimethylamino)phenyl)(hydroxy)(phenyl)methyl)phenoxy)ethan-1-ol

Chemical Property of 2-(4-((4-(dimethylamino)phenyl)(hydroxy)(phenyl)methyl)phenoxy)ethan-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4-((4-(dimethylamino)phenyl)(hydroxy)(phenyl)methyl)phenoxy)ethan-1-ol

There total 1 articles about 2-(4-((4-(dimethylamino)phenyl)(hydroxy)(phenyl)methyl)phenoxy)ethan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

2-(4-bromophenoxy)ethanol (34743-88-9) + 4-(Dimethylamino)benzophenone (530-44-9) → 2-(4-((4-(dimethylamino)phenyl)(hydroxy)(phenyl)methyl)phenoxy)ethan-1-ol (1609033-85-3)

Guidance literature:

2-(4-bromophenoxy)ethanol; With n-butyllithium; In tetrahydrofuran; hexane; at -70 ℃; for 0.5h; Inert atmosphere;

4-(Dimethylamino)benzophenone; In tetrahydrofuran; hexane; at -70 - 20 ℃; for 2h; Inert atmosphere;

DOI:10.1016/j.tetlet.2014.03.139

Reference yield: 32.0%

2-(4-((4-(dimethylamino)phenyl)(hydroxy)(phenyl)methyl)phenoxy)ethan-1-ol (1609033-85-3) + Thioctic acid (1077-28-7,62-46-4) → C31H37NO4S2 (1609033-86-4)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 0 - 20 ℃; for 1h;

DOI:10.1016/j.tetlet.2014.03.139

upstream raw materials:

2-(4-bromophenoxy)ethanol

4-(Dimethylamino)benzophenone

Downstream raw materials:

C₃₁H₃₇NO₄S₂