4-methoxy-1-tetradecylbenzene

Base Information

• Chemical Name: 4-methoxy-1-tetradecylbenzene
• CAS No.: 22165-05-5
• Molecular Formula: C₂₁H₃₆O
• Molecular Weight: 304.516
• Mol file: 22165-05-5.mol

Synonyms:4-methoxy-1-tetradecylbenzene

Chemical Property of 4-methoxy-1-tetradecylbenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 4-methoxy-1-tetradecylbenzene

There total 9 articles about 4-methoxy-1-tetradecylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

tetradec-7-ene (10374-74-0) + para-iodoanisole (696-62-8) → 4-methoxy-1-tetradecylbenzene (22165-05-5)

Guidance literature:

tetradec-7-ene; With Schwartz's reagent; In tetrahydrofuran; at 50 ℃; for 24h; Inert atmosphere; Sealed tube;

para-iodoanisole; With 4,4'-di-tert-butyl-2,2'-bipyridine nickel(II) bromide; triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 24h; Inert atmosphere; Irradiation; Sealed tube;

DOI:10.1016/j.chempr.2019.12.010

Reference yield: 62.0%

4-methoxyphenyl p-toluenesulfonate (3899-91-0) + n-tetradecylmagnesium chloride (110220-87-6) → 4-methoxy-1-tetradecylbenzene (22165-05-5)

Guidance literature:

With 1,2-bis(diphenylphosphino)ethane nickel(II) chloride; In tetrahydrofuran; at 65 ℃; Inert atmosphere; Schlenk technique;

DOI:10.1002/adsc.201801586

Reference yield: 52.0%

1-bromo-4-methoxy-benzene (104-92-7) + 1-Bromotetradecane (112-71-0) → 4-methoxy-1-tetradecylbenzene (22165-05-5)

Guidance literature:

1-bromo-4-methoxy-benzene; With tert.-butyl lithium; In tetrahydrofuran; hexane; at -78 ℃; for 2h; Inert atmosphere;

1-Bromotetradecane; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 48h;

DOI:10.1039/c4tc00533c

upstream raw materials:

1-(4-methoxy-phenyl)-tetradecan-1-one

1-bromo-4-methoxy-benzene

1-iodotetradecane

methoxybenzene

Downstream raw materials:

3-(4-tetradecylphenoxy)-1,2-propanediol

3-(3-tetradecylphenoxy)-1,2-propanediol

2,2-dimethyl-4-<(4-tetradecylphenoxy)methyl>-1,3-dioxolane

1-[(4-methoxyphenyl)diphenylmethoxy]-3-(3-tetradecylphenoxy)-2-propanol